Меню
Идёт набор NCT07178288

Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

Без фазы С лечением Tennis Elbow Health Adult Subjects Lateral Elbow Tendinopathy (Tennis Elbow) Pressure Pain Threshold (PPT)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Physiological/measurement-validation study.
Кому может быть актуально
Состояния в реестре: Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT). Базовые параметры: до 60 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Иордания
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

Measurement Properties and Temporal Stability of Conditioned Pain Modulation in Individuals With and Without Lateral Epicondylalgia

Обзор

This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) tested with a handheld device that slowly increases pressure on standard spots near the elbow and wrist; they say when it first becomes painful. To test the body's built-in anti-pain system (conditioned pain modulation, CPM), one hand is placed in ice water (the cold-pressor task) and PPT is measured again at set times (before, during, and after the cold stimulus) to see how much pain sensitivity changes and how long that change lasts. Both PPT reliability and CPM after effect are measured in this study. The study findings may help improve future assessment and treatment of musculoskeletal pain conditions.

Подробное описание

This is a quasi-experimental reliability and time-course study using digital algometry for PPT and the cold-pressor task for CPM. Primary outcomes include PPT reliability (with intraclass correlation coefficient (ICC), standard error of measurement (SEM), and smallest detectable change (SDC) and the duration of CPM after-effects (time to return toward baseline). Testing is planned in the Physiotherapy Clinic at the Community Rehabilitation Center, with a minimum sample noted in the application. The protocol emphasizes standardized sites, repeated measures at predefined time points, and storage of coded data on university systems.

Вмешательства

  • Другое Physiological/measurement-validation study
    Protocols PPT Reliability The assessor measured Pressure Pain Threshold; PPT, using an electronic digital algometer. Measurements will be taken at two test sites wrist at baseline, at 1, 3 and 5 minutes. Three PPT measurements were taken at each time point with a 15-20 seconds interval between each. Mean values will then be used in analysis. Conditioned Pain Modulation In order to assess CPM, PPT was used as a tested stimulus on the painful arm (elbow and wrist). Baseline PPTs will assessed thr

Первичные конечные точки

  • Pressure Pain Threshold (PPT) [Срок оценки: The PPT session would take about 30min to be completed in one day.]
  • Conditioned Pain Modulation (CPM) [Срок оценки: 1 and half hours in a separate day (different to the PPT session day)]

Критерии участия

TE Group

Критерии включения

Patients with Tennis Elbow confirmed at initial assessment by the Primary Investigator (PI)

Unilateral elbow pain > 6 weeks duration reproduced on at least two of the following tests:

  • Palpation of the lateral epicondyle
  • Isometric testing of the wrist extensors
  • Middle finger extension test
  • Passive stretch of wrist extensors
  • Resisted hand gripping using a dynamometer
  • Upper limb neurodynamic test-radial nerve bias (ULNDT-RN)

Критерии исключения

  • History of chronic pain conditions (e.g. fibromyalgia, irritable bowel
  • syndrome, temporomandibular dysfunction, migraines)
  • Neurological or sensory dysfunction (especially in the upper limbs)
  • History of chronic musculoskeletal pain (e.g. arthritis, chronic low back
  • pain)
  • Contraindications to cold application (i.e. Reynaud's disease, diabetes)
  • Current or long-term use of pain medication or anti-depressants

Healthy Group The asymptomatic group included adults (18-65 years) without pain (acute or chronic) at least 3 months before the experimental sessions.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Не применимо
Модель
Одна группа
Маскирование
Открытое
Основная цель
Другое

Центры проведения

Иордания · 1 центр
  • The Hashemite University, Department of Physical Therapy; Community Rehabilitation Center — Zarqa

Публикации

  • Oono Y, Nie H, Matos RL, Wang K, Arendt-Nielsen L. The inter- and intra-individual variance in descending pain modulation evoked by different conditioning stimuli in healthy men. Scand J Pain. 2011 Oct 1;2(4):162-169. doi: 10.1016/j.sjpain.2011.05.006. PMID 29913755
  • Bilika P, Kalamatas-Mavrikas P, Vasilis N, Strimpakos N, Kapreli E. Reliability of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) in Participants with and without Chronic Shoulder Pain. Healthcare (Basel). 2024 Aug 31;12(17):1734. doi: 10.3390/healthcare12171734. PMID 39273758

Идентификаторы

NCT: NCT07178288 · 32/1/2024/2025

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗