Efficacy of Serratus Posterior Superior Intercostal Plane Block on Post-operative Pain in Cardiac Surgery.
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Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: conventional opioid-based technique, SPSIPB Group.
- Кому может быть актуально
- Состояния в реестре: Postoperative Pain, Cardiac Surgery. Базовые параметры: 18 лет — 60 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Египет
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Efficacy of Serratus Posterior Superior Intercostal Plane Block on Post-operative Pain Management in Patients Undergoing Adult Cardiac Surgery. A Randomized Controlled Trial
Обзор
Cardiac surgery, particularly procedures involving median sternotomy, is associated with significant postoperative pain. Acute postoperative pain is severe in cardiac patients undergoing sternotomy, and pain intensity is more severe than expected. Poorly controlled pain after surgery can lead to myocardial ischemia and pulmonary infections.Regional anesthesia techniques offer a promising alternative or adjunct to systemic opioids, providing targeted pain relief with fewer systemic side effects. The Serratus Posterior Superior Intercostal Plane Block (SPSIPB) is a novel regional anesthesia technique that involves injecting local anesthetic into the fascial plane between the serratus posterior superior muscle and the intercostal muscles
Подробное описание
Cardiac surgery, particularly procedures involving median sternotomy, is associated with significant postoperative pain. Acute postoperative pain is severe in cardiac patients undergoing sternotomy, and pain intensity is more severe than expected. Poorly controlled pain after surgery can lead to myocardial ischemia and pulmonary infections.
Effective pain management is crucial for patient recovery, reducing complications, and facilitating early mobilization. Opioids are commonly used for postoperative analgesia but are associated with numerous side effects, including respiratory depression, nausea, vomiting, constipation, and prolonged hospitalization.
Regional anesthesia techniques offer a promising alternative or adjunct to systemic opioids, providing targeted pain relief with fewer systemic side effects. The Serratus Posterior Superior Intercostal Plane Block (SPSIPB) is a novel regional anesthesia technique that involves injecting local anesthetic into the fascial plane between the serratus posterior superior muscle and the intercostal muscles. This block will provide analgesia to the anterolateral and posterior chest wall, covering dermatomes relevant to cardiac surgery.
Preliminary case reports and small studies suggest its efficacy in thoracic and cardiac surgeries, demonstrating effective pain control and reduced opioid consumption. However, a randomized controlled trial is necessary to definitively determine the efficacy and safety of SPSIPB as part of multimodal analgesia in adult cardiac surgery.
Fascial plane blocks in regional anesthesia have gained importance in recent years. It involves injection into a tissue plane to provide analgesia and is an alternative to neuraxial and paravertebral techniques. It is often safer and is associated with less cardiorespiratory instability or complications compared to epidural analgesia.
The primary objective of the study is to examine the effect of adding preemptive SPSIPB to general anesthesia in adult cardiac surgery through sternotomy on the postoperative opioid consumption. The secondary objectives will include time to extubation, the intensity of postoperative pain, time to 1st rescue analgesia, patient satisfaction, and any possible side effects of the study drugs and technique.
Вмешательства
- Процедура conventional opioid-based technique
Control Group: Participants will receive general anaesthesia with a conventional opioid-based technique - Процедура SPSIPB Group
SPSIPB Group: Participants will receive an ultrasound-guided Serratus posterior superior intercostal plane block with 30 ml 0.25% bupivacaine per side pre-incision and general anaesthesia with opioid based fentanyl
Первичные конечные точки
- Total postoperative fentanyl consumption [Срок оценки: the first 24 and 48 hours post-extubation.]
Вторичные конечные точки (6)
- Time to extubation [Срок оценки: post operative 6 hour]
- Time to first rescue analgesia [Срок оценки: 48hour post operatively]
- Postoperative pain intensity [Срок оценки: 6, 12, 18,24, 36, and 48 hours post-extubation.]
- Patient satisfaction [Срок оценки: at 24 hours post-extubation]
- Length of stay [Срок оценки: post operative 5 days]
- Incidence of adverse [Срок оценки: 28hour postoperative]
Критерии участия
Критерии включения
- aged 18 to 60
- both sexes
- who are scheduled to have fast-tracking elective on-pump cardiac surgery through a median sternotomy,
- American Society of Anesthesiologists Physical status II-III,
- Ability to understand and provide informed consent
Критерии исключения
- patients who refused to participate in the study,
- who had Cognitive impairment or mental disorders,
- Ages <18 and >60 years,
- BMI <18 and >35,
- patients with puncture site infection,
- patients who documented allergy to local anesthetic drugs,
- patients used to take chronic pain medications, patients who made previous sternotomy or chest surgery
- patients with a history of substance abuse.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Тройное слепое
- Основная цель
- Профилактика
Центры проведения
Египет · 1 центр
- Faculty of medicine ,Alexandria university — Alexandria
Идентификаторы
NCT: NCT07175298 · 0307518