Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

Официальное название

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis - Aims 2 and 3

Обзор

The goal of this pilot hybrid type I efficacy/implementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis (NMS). Results from this pilot will inform the design of a future larger effectiveness trial of the decision support tool. Participants will either receive usual care or receive the decision support tool. Researchers will assess the decision made, decision quality, individual affective, cognitive, and behavioral effects, and feasibility and acceptability of tool use. They will also collect potential barriers and facilitators to implementation and feedback about the tool and study design to maximize likelihood of successful deployment of the tool into clinical practice and inform the design of a future trial. The outcomes measures will be used to inform potential effect size estimates to inform a future trial.

Подробное описание

Neuromuscular scoliosis (NMS) can result in severe disability for children. Non-operative management including bracing and physical therapy minimally slows scoliosis progression, but operative management with posterior spinal fusion (PSF) carries high risks of morbidity and mortality in part due to the multiple comorbid conditions seen in children with NMS. Decisions like PSF that have no clear best treatment option are best served by shared decision making (SDM). SDM is a collaborative process where patients, parents, and providers share their knowledge, preferences, and values to reach treatment plan agreement. Our prior qualitative study creating a framework of SDM for children with multiple comorbid conditions like children with NMS found that parents face immense decision related uncertainty that often goes unacknowledged by providers and that parents and providers struggle with identifying and communicating family preferences and values that are important for treatment decision making. Our prior work has identified optimal methods to communicate uncertainty and identified the preferences and values parents of children with NMS have when it comes to treatment decision making for NMS. This study will pilot test a decision support tool that contains these elements.

Вмешательства

• Поведенческое Decision support tool
  Decision support tool developed for patients, parents, and providers of children with neuromuscular scoliosis

Первичные конечные точки

• Intention for NMS treatment [Срок оценки: Immediately after clinic visit]

Вторичные конечные точки (12)

• Intention for NMS treatment [Срок оценки: Immediately after clinic visit]
• Intention for not delaying treatment [Срок оценки: Immediately after clinic visit]
• Knowledge questions [Срок оценки: Immediately after clinic visit]
• Acceptability of intervention [Срок оценки: Immediately after clinic visit]
• Physician trustworthiness [Срок оценки: Immediately after clinic visit]
• Feasibility of intervention [Срок оценки: Immediately after clinic visit]
• Risk perception [Срок оценки: Immediately after clinic visit]
• Decision conflict [Срок оценки: Immediately after clinic visit]
• Decision readiness [Срок оценки: Immediately after clinic visit]
• Acceptability of Intervention- Qualitative [Срок оценки: Within 3 months of clinic visit (for parents) and at end of study, approximately within 18 months of consent (for providers).]
• Worry [Срок оценки: Immediately after clinic visit]
• Quality of shared decision making [Срок оценки: Immediately after clinic visit]

Критерии участия

Критерии включения

• Parent-child dyads of children with neuromuscular scoliosis who speak English and Spanish.
• Child is between ages 8-21 years of age and they are coming into the pediatric orthopaedic surgery clinic for consultation about potential surgery for NMS.
• NMS is defined as having neurologic impairment (NI) and scoliosis using relevant ICD-9 or ICD-10 codes from Feudtner, et al. 2014 or Berry, et al. 2012. or a qualifying diagnosis per the Pediatric Spine Study Group definition of NMS.
• All pediatric orthopaedic surgeons and neurosurgeons who treat neuromuscular scoliosis at our study sites will be eligible participants.

Критерии исключения

• Families whose child with NMS is less than 8 years of age at time of orthopaedic consultation because surgery at a younger age usually indicates an atypical case.
• Children with the diagnosis of Duchenne's or Becker's muscular dystrophy due to potential disease modifying therapies that may alter curve progression.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Нерандомизированное

Модель

Перекрёстный дизайн

Маскирование

Открытое

Основная цель

Организация здравоохранения

Центры проведения

США · 2 центра

• Children's Hospital Los Angeles — Los Angeles
• University of Utah — Salt Lake City

Идентификаторы

NCT: NCT07167927 · IRB_00169930 · 1K23AR079778

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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