Набор скоро начнётся NCT07165574

Prevalence of Anticholinergics in Geriatric Patients With Acute Functional Deterioration

— Наблюдательное Frailty in Older Adults Functional Decline Anticholinergic Syndrome

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: No intervention as the study is observational.
Кому может быть актуально: Состояния в реестре: Frailty in Older Adults, Functional Decline, Anticholinergic Syndrome. Базовые параметры: Без ограничений · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Дания
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

This study investigates the anticholinergic burden on patients seen in the Subacute mobile outpatient geriatric clinic in Aalborg, Denmark, between the years of 2024 and 2025. The age demographic in Denmark and multiple other countries is changing rapidly, with more old and very old individuals as a result. As humans become older, they tend to accumulate more illnesses, and the risk of polypharmacy increases. There is a wide selection of medicine that affect the binding of acetylcholine to the muscarinic receptors, which is either the intended function of the pharmacological product or a side effect. Since there is no built-in feature in computer systems used by doctors to calculate the cumulative anticholinergic burden, it is often not recognized, thus not reflected upon. This raises concerns about potential central and peripheral side effects, such as altered mental status, visual disturbances, tachycardia, urinary and fecal retention, dry skin etc. The study aims to determine the prevalence of anticholinergics in the last 100 patients seen by the Subacute mobile outpatient geriatric clinic in Aalborg University Hospital. The patients are placed in municipal extended-care facilities. Furthermore, the study will investigate the prevalence of anticholinergic side effects concerning the burden on this population. The study is a retrospective chart review of patient charts from the years of 2024 and 2025, analyzing patient characteristics, comorbidities, medication lists, and calculating the anticholinergic burden through the ACB calculator.

Вмешательства

Другое No intervention as the study is observational
As this is an observation study, participants are not assigned an intervention as part of the study

Первичные конечные точки

Prevalence of anticholinergics [Срок оценки: Day 1. That is on the day of patients first contact with the subacute outpatient geratric function at Aalborg Unviversity Hospital]

Вторичные конечные точки (2)

Prevalence of central side effects [Срок оценки: On the day of patients first contact with the subacute outpatient geratric function at Aalborg Unviversity Hospital]
Prevalence of peripheral anticholinergic side effects [Срок оценки: On the day of patients first contact with the subacute outpatient geratric function at Aalborg Unviversity Hospital]

Критерии участия

Критерии включения

patients seen by the Subacute outpatient geriatric clinic at Aalborg University hospital, Denmark, between 2024 and 2025.
Consecutive sampling starting with the most recent patient chart and going backwards.
Inclusion is based on chart review and all patients are therefore included consecutively.