Идёт набор NCT07163858

Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

Без фазы С лечением Coronary Artery Disease With Need for Bypass Surgery Coronary Artery Disease(CAD) Coronary Artery Bypass Off Pump Coronary Artery Bypass Graft

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: passive leg raising for hemodynamic management during open-heart coronary bypass grafting, Use of Noradrenaline only in control group.
Кому может быть актуально: Состояния в реестре: Coronary Artery Disease With Need for Bypass Surgery, Coronary Artery Disease(CAD), Coronary Artery Bypass, Off Pump Coronary Artery Bypass Graft. Базовые параметры: от 18 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Франция
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Comparison of Hemodynamic Management by Postural Mobilization Versus Chemical Vasoconstriction Using Noradrenaline Exclusively in Off-pump Coronary Artery Bypass Graft Surgery: A Prospective, Randomized, Comparative, Single-center Study.

Обзор

This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.

Подробное описание

OPTICAB is a single-site study in France that aims to compare two hemodynamic management techniques during off-pump coronary artery bypass graft (CABG) surgery: postural mobilization (+/- noradrenaline) versus noradrenaline only. Primary objective is to evaluate how often noradrenaline is needed when managing hemodynamics using postural mobilization (passive leg raising) during off-pump CABG surgery. The study will also compare revascularization rate and post-operative complications among both groups, and assess perioperative hemodynamic management during the 30-day follow up period.

Вмешательства

Процедура passive leg raising for hemodynamic management during open-heart coronary bypass grafting
Passive leg raising will be used in the experimental group in order to manage hemodynamics: legs will be raised to an angle of approx. 45°
Процедура Use of Noradrenaline only in control group
Noradrenaline will be used for hemodynamic management. Passive leg raising will not be used in this group

Первичные конечные точки

Assess use of noradrenaline in the experimental group (postural mobilization) vs control group (NA only) for hemodynamic management during open-heart coronary bypass graft surgery. [Срок оценки: From beginning to end of urgery]

Критерии участия

Критерии включения

Adult patient
patient requiring isolated coronary bypass surgery
Elective procedure or medical emergency
First cardiac surgery
Patient with an EF ≥30%
Mandatory affiliation to a social security system
Signed informed consent form
Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure