Drumming Lessons' Influence on Children With Down Syndrome

Официальное название

Effects of Drumming Lessons on Brain and Behavior in Children With Down Syndrome

Обзор

The goal of this clinical trial is to learn if drumming lessons can increase self-control in children with Down syndrome. The main question it aims to answer is whether 2 months of drumming lessons can improve the behavioral control and timing skills in children with Down syndrome. Participants are between 7 and 15 years of age and receive two months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome. Children in the experimental group visit our lab once before lessons start and once after lessons are completed. Children in the control group visit our lab twice before they start their lessons. Lab visits include brain recordings taken using a net-style cap, computer tasks, and drumming to music.

Подробное описание

Down syndrome (DS) is the most common chromosomal cause of cognitive disability, and it affects approximately 1 in 700 live births. Although the genetic etiology of DS (a complete or partial third 21st chromosome) has been known for over 50 years, many fundamental questions about how to support high quality of life for individuals with DS remain unanswered. One area of relative weakness in DS is Inhibitory Control (IC). This skill is important for daily tasks such as following directions, making decisions, and managing money among other tasks. Existing research demonstrates a clear link between playing the drums and IC. In the proposed research, we will conduct an experiment in which 7- to 12-year-old children are randomly assigned to the Experimental (EXP) and Wait List Control (WLC) conditions. In the EXP condition, children will receive drumming lessons between Visit 1 and Visit 2, and in the Wait List Control group, children will receive drumming lessons after Visit 2. In this way, all children will receive drumming lessons, but only the EXP group will show effects of the drumming lessons in Visit 2. Testing conducted during Visits 1 and 2 will include behavioral and neural measures of inhibitory control and drumming, neural measures of beat perception, and parent report of social behavior (via Standardized questionnaire). Our predictions are that children in the EXP condition will show improvements in both measures of IC and increases in precision in the beat perception and drumming tasks. We also expect that parent report of children's behavior on the social skills questionnaire will show improvement. Across the EXP and WLC conditions, we expect no differences at Visit 1 but significant differences between conditions at Visit 2.

Вмешательства

• Поведенческое 2 months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome
  Drumming lessons consisting of how to use hands to drum on djembe drum, using alternating hands to drum, drumming to a metronome and to music.
• Поведенческое Lessons after measurement
  Receiving lessons after the two lab visits should still offer any possible positive effects to participants while still allowing us to compare the Control group children's behaviors to those of the Experimental group.

Первичные конечные точки

• Zoo task [Срок оценки: Baseline to two months]
• Statue task [Срок оценки: Baseline to two months]
• Beat Perception [Срок оценки: Baseline to two months]
• Beat production [Срок оценки: Baseline to two months]

Критерии участия

Критерии включения

• Down syndrome

Критерии исключения

• Already taken drumming lessons
• Uncorrected hearing loss
• Uncorrected vision loss

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Фундаментальное исследование

Центры проведения

США · 1 центр

• Vanderbilt University — Nashville

Публикации

• Cahart MS, Amad A, Draper SB, Lowry RG, Marino L, Carey C, Ginestet CE, Smith MS, Williams SCR. The effect of learning to drum on behavior and brain function in autistic adolescents. Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2106244119. doi: 10.1073/pnas.2106244119. Epub 2022 May 31. PMID 35639696

Идентификаторы

NCT: NCT07156318 · 230465

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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