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Идёт набор NCT07136441

Sciatic Nerve Stiffness Using Two-Sequences of Lower Limb Neurodynamic Testing: A Shear Wave Elastography Study

— Наблюдательное Sciatic Nerve

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Lower Limb Neurodynamic Test (LLNT) with Shear Wave Elastography.
Кому может быть актуально
Состояния в реестре: Sciatic Nerve. Базовые параметры: 25 лет — 40 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Египет
Следующий шаг
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Обзор

The purposes of the study are: 1. To measure differences in Sciatic nerve (SN) stiffness using shear-wave elastography (SWE) during two movement sequences of the lower limb neurodynamic test (LLNT) in low back pain with sciatica. 2. To measure differences in Sciatic nerve stiffness using shear-wave elastography during two movement sequences of the lower limb neurodynamic test in control group. 3. To compare difference in Sciatic nerve stiffness using shear-wave elastography during two movement sequences of the lower limb neurodynamic test between low back pain patients with sciatica and control group.

Подробное описание

As peripheral nerves can exhibit regional variations in their anatomy and mechanical properties, investigating the response of different nerve segments to different loading patterns based on the order of joint movement will provide a better understanding of nerve biomechanics during neurodynamic testing.

This may help optimize the lower limb neurodynamic test (LLNT) application for different pathological situations and potentially increase its diagnostic capacity to detect localized alterations in a specific nerve segment such as sciatica.

Ultrasonography does not have the sensitivity required to detect all forms of peripheral nerve disorders and fails to provide information about nerve mechanical properties such as stiffness.

By using neurodynamic sequencing, clinicians may direct neural stress toward targeted areas suspected of involvement and, at the same time, perform the test with reduced load on more remote nerve segments. The ability to modify neural load distribution during the LLNT could play an interesting role in differential diagnosis, when symptoms present similar characteristics but have different regional origin.

There is a gap in the literature concerning the measurement of (SWV) of sciatic nerve during LLNT proximal (LLNT-PROX) to distal and from distal (LLNT\_DIST) to proximal sequences of LLNT.

Вмешательства

  • Диагностический тест Lower Limb Neurodynamic Test (LLNT) with Shear Wave Elastography
    Participants underwent sciatic nerve stiffness assessment using shear wave elastography during two distinct sequences of the lower limb neurodynamic test. Each participant received: Proximal-to-distal sequence: Starting with hip flexion, followed by knee extension, then ankle dorsiflexion with toe extension. Distal-to-proximal sequence: Starting with ankle dorsiflexion and toe extension, followed by knee extension, then hip flexion.

Первичные конечные точки

  • Shear Wave Velocity (SWV) measured in meters per second (m/s) [Срок оценки: 20 minutes, During a single assessment session at baseline]

Критерии участия

Критерии включения

  • Thirty participants ranging in age from 25 to 40 years from both genders with a diagnosis of low back pain with radiating leg pain and thirty control group.
  • The main symptoms are low back pain with unilateral leg pain(sciatica) for 3-12 months for group A.
  • Patients with lumbar disc herniation (L4-5) with diagnostic imaging as MRI for group A.
  • Positive straight leg raising are considered for inclusion in the study for group A.
  • Control group must be free from any symptoms of nerve irritation or compression, with normal neurological examination findings, including reflexes, sensation, negative straight leg raising and motor strength.

Критерии исключения

  • Diabetes mellitus.
  • Any type of polyneuropathy
  • Trauma of lumbar spine
  • Previous history of back surgery
  • Piriformis syndrome.
  • Participants with conditions that reduce image quality on US imaging (thick gluteal subcutaneous fat tissue.
  • Hip joint prosthesis.
  • Professional athletes (Neto et al., 2024).
  • Skin infection

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Модель наблюдения
Случай-контроль

Центры проведения

Египет · 1 центр
  • Cairo University — Giza

Идентификаторы

NCT: NCT07136441 · P.T.REC/012/005897

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗