Improving Adherence to COPD Treatments in Primary Care

The investigators hypothesize that a primary care physician-directed intervention, consisting of a seminar with up-to-date professional guidance and motivational interviewing course, would result in patients' higher adherence to treatment, improved care, and fewer COPD exacerbations.

The study aims:

1. To evaluate the effect of specific COPD patient centric educational program for primary care physicians on adherence to recommended therapy. 2. To evaluate the effect of specific COPD patient centric educational program for primary care physicians on the number of moderate and severe COPD exacerbations.

This is a two-arm, parallel, randomized controlled trial conducted in a primary care setting, involving primary care physicians. All physicians will sign an informed consent form to participate.

The study will include two groups:

1. Intervention Group - Twenty primary care physicians will be recruited. After inclusion and signing an informed consent, all physicians will participate in a two-day seminar. The seminar will include: up-to-date professional guidance on COPD management, an inhalers workshop and a course of motivational interview. The physicians will undergo a refresher workshop 3 months after entering the study, and visual and informative newsletter will be sent to them every 3 months. 2. Control Group - Twenty primary care physicians, matched to the intervention group by sociodemographic area and number of COPD patients in past year.

The effect of the intervention will be assessed based on the outcomes of all COPD patients that visited one of the physicians in the intervention/control groups during the first 6 months after study initiation. These patients will be identified retrospectively from medical charts. Assessment of patient care and outcomes will be analyzed retrospectively, 18 months after study initiation (end of study), addressing each patient's first 12 months from first relevant clinic visit.

Randomization of primary care physicians to each group will be performed with stratification to the number of registered individual COPD patients for each physician. In addition, randomization will be performed with blocks of clinics from areas of similar sociodemographic characteristics.

COPD medication adherence rates vary by geographic location but are usually around 25-30%. Based on previous research, the investigators conservatively assume that our intervention will lead to an absolute 17% increase in adherence during the 12 months from first follow-up. Considering the above, to achieve an alpha of 0.05 and a power of 80%, there is a need for 127 patients in each group. Given that participating primary care physicians must have seen at least 18 individual COPD patients in the past year, and assuming a similar rate of visits during the follow-up period, along with a 15-20% loss-to-follow-up due to changes in the treating physician, the investigators estimate that 20 primary care physicians will be needed in each group.

• Change in adherence to inhaler therapy pre-post study [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Non-inhaler medications adherence pre-post study [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Non-inhaler medication adherence [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Annualized rate of moderate or severe COPD exacerbations [Срок оценки: From first patient visit after study initiation to 12 months after.]
• All-cause mortality [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Cardiovascular events [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Guideline-based treatment [Срок оценки: From first patient visit after study initiation to 12 months after.]
• Physician knowledge on COPD [Срок оценки: From first patient visit after study initiation to 12 months after.]