Prison-Based HIV Partner Notification

Обзор

Assisted partner notification (APN) is a voluntary and confidential process that utilizes specially-trained health workers to encourage and assist people diagnosed with HIV to inform their sex and drug use partners about possible shared exposure to HIV. With APN, partners who have come in contact with HIV are notified about exposure and given information to protect themselves from contracting HIV in the future or to begin treatment, if needed. This study compares two types of HIV partner notification. Incarcerated men with HIV will be recruited as "index participants". Participants in both groups will be encouraged to notify sex and needle-sharing partners with whom they may have shared an HIV exposure before incarceration. All participants have the option to self-notify partners during a prison visitation or telephone call. In addition, participants randomized to an APN Choice group also can opt for anonymous notification by specially-trained APN notifiers that includes contact tracing if needed. As outcomes, we will compare the number of partners in each condition who are notified, HIV tested, diagnosed, and linked to HIV treatment. The study will show if prison-based APN is successful in reaching partners for HIV testing.

Подробное описание

This study will evaluate the effectiveness of Impart, an assisted partner notification (APN) intervention that was developed to increase HIV testing and referral into treatment among the sex and drug use partners of incarcerated people with HIV. Incarcerated people with HIV are assigned randomly to one of two groups. Participants assigned to the Impart Choice condition may choose to inform partners themselves by telephone or in person or they may ask specially-trained nurses and outreach workers to confidentially notify partners and to offer partners HIV testing. Meanwhile, participants assigned to the Standard of Care Self-Tell Notification Only condition will be encouraged to tell their partner(s) themselves, either by phone or in person during a prison visitation. As outcomes, we will compare after six weeks the number of partners in each condition who are notified, HIV tested, diagnosed, and linked to confirmatory HIV testing and treatment After 6 weeks, we will offer outreach-assisted partner notification to any participant who was randomized to or initially chose to notify their partners themselves. Results from the study will provide evidence as to the use of prison-based APN in making partner notification desirable and acceptable to people in prison while also reducing barriers to partner notification and HIV testing for their partners in the community.

Вмешательства

• Поведенческое Impart Assisted Partner Notification
  Participants randomized to the Impart arm may choose per partner either a) sell-tell notification or b) having an Impart-trained APN notifier team locate, notify, and offer HIV testing to their partners without revealing the identity of who had named them. Impart notifiers initially contact named partners by telephone and identify themselves as health service providers with important information about the partner's health that needs to be shared in person. Partners who agree to meet are asked to
• Поведенческое Self-Tell Notification
  Participants who wish to self-notify one or more partners are coached to do so either in person or by telephone. APN counselors confirm the names of partners for whom participants provide contact information before giving the phone to the participant to explain the reason for the call: "I want to speak with you because I was diagnosed with HIV and I believe we shared an exposure." Alternately, participants who wish to notify partners in person are coached to inform partners that they have a seri

Первичные конечные точки

• HIV Testing [Срок оценки: 6 weeks after randomization]

Вторичные конечные точки (5)

• HIV Notification [Срок оценки: 6 weeks post-randomization]
• First HIV Test [Срок оценки: 6 weeks post-randomization]
• HIV Diagnosis [Срок оценки: 6 weeks post-randomization]
• ART Linkage [Срок оценки: 6 weeks post-randomization]
• ART Initiation [Срок оценки: 6 weeks post-randomization]

Критерии участия

Критерии включения

• HIV-diagnosed
• Sexually active (penile-vaginal or penile-anal) and/or sharing injection equipment during the year before incarceration

Критерии исключения

• Incarcerated more than 5 years

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Двойное слепое

Основная цель

Скрининг

Центры проведения

Индонезия · 1 центр

• Fakultas Ilmu Keperawatan, Universitas Indonesia — Depok

Публикации

• Culbert GJ, Levy JA, Steffen AD, Waluyo A, Earnshaw VA, Rahadi A. Impart: findings from a prison-based model of HIV assisted partner notification in Indonesia. J Int AIDS Soc. 2023 Jun;26(6):e26132. doi: 10.1002/jia2.26132. PMID 37339342
• Culbert GJ, Waluyo A, Levy JA, Steffen AD, Earnshaw VA, Rahadi A. Prison-based HIV partner notification in Indonesia: rationale and design of a hybrid type 1 effectiveness-implementation study. BMC Public Health. 2026 Mar 16;26(1):1321. doi: 10.1186/s12889-026-26950-z. PMID 41840552

Идентификаторы

NCT: NCT07103928 · 2024-0926 · R01MH138246

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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