Glycemic Improvement With Team, Technology, Education and Peer Resources in Type 1 Diabetes-GLITTER Study

Patients with type 1 diabetes (T1D) face significant glycemic fluctuations, posing substantial challenges in disease management. Current clinical evidence indicates that although interventions such as structured education programs, peer support, and novel diabetes technologies demonstrate positive outcomes when applied individually, the glycemic target attainment rate remains suboptimal, with fewer than 30% achieving this benchmark. To address this clinical dilemma, the investigators has proposed the GLITTER (Glycemic Improvement with Team, Technology, Education and Peer Resources in type 1 diabetes) study, which aims to establish a four-in-one integrated management model combining multidisciplinary collaborative teams, structured educational frameworks, peer support systems, and diabetes technologies. The research team comprises T1D-specialized physicians and diabetes educators. Structured education is delivered through dedicated T1D specialty clinics and by local clinicians. Technological support involves informing patients about access to continuous glucose monitors (CGM) and insulin pumps without mandating their use, while peer support is established through patient communication groups (volunteer matching mechanisms are not yet implemented). This GLITTER study seeks to achieve dual objectives: population-wide coverage and whole-disease-course management for individuals with T1D.

This is a multicenter, prospective, cohort study. This longitudinal investigation systematically collects multidimensional clinical datasets encompassing glycemic control parameters, pancreatic β-cell function, and complication risk profiles through regular follow-up visits. This study explores the metabolic control, psychological outcomes, and their associated influencing factors among patients with T1D.

• Percentage of patients using continuous glucose monitors [Срок оценки: Trough study completion, an average of 1 year]
• Percentage of patients using insulin pump [Срок оценки: Trough study completion, an average of 1 year]
• Diabetes-related complications [Срок оценки: Trough study completion, an average of 1 year]
• Urine Albumin-to-Creatinine Ratio [Срок оценки: Trough study completion, an average of 1 year]
• Change in titer of autoantibodies [Срок оценки: Trough study completion, an average of 1 year]
• Change in C-peptide [Срок оценки: Trough study completion, an average of 1 year]
• Change in blood glucose [Срок оценки: Trough study completion, an average of 1 year]
• Systolic blood pressure [Срок оценки: Trough study completion, an average of 1 year]
• Diastolic blood pressure [Срок оценки: Trough study completion, an average of 1 year]
• Change in lipid profiles [Срок оценки: Trough study completion, an average of 1 year]
• Self-Management of Type 1 Diabetes for Chinese Adults [Срок оценки: Trough study completion, an average of 1 year]
• 23-item Chinese Version of Self-Report Measure of Self-Management of Type 1 Diabetes for Adolescents [Срок оценки: Trough study completion, an average of 1 year]