The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Knee extension exercise.
- Кому может быть актуально
- Состояния в реестре: Ageing, Muscle Fatigue Caused by Repetitive Muscle Exercise. Базовые параметры: от 19 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Канада
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Не всё понятно в терминах? Прочитайте наш гид для пациентов →
Официальное название
Age-Related Differences in Skeletal Muscle Endurance Responses to Various Relative Loads of Dynamic Resistance Exercise With and Without Peripheral Blood Flow Occlusion
Обзор
The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes. To answer this question, we are comparing how many repetitions of a leg exercise (knee extensions) younger and older adults can do at different exercise intensities. We will also look at how the muscles use oxygen during these exercises. Participants will take part in 12 different exercise sessions. In each session, they will perform as many knee extensions as possible using different amounts of weight-consisting of 20%, 30%, 40%, 50%, 60% and 70% of the maximum weight they can lift one time. Each weight will be tested both with and without a cuff on the leg that temporarily reduces blood flow to the muscle.
Вмешательства
- Другое Knee extension exercise
Maximum repetitions of knee extension exercise at 20%, 30%, 40%, 50%, 60% and 70% of participants one rep max with and without blood flow occlusion
Первичные конечные точки
- Maximum repetitions performed during knee extension exercise [Срок оценки: From enrollment to the end of the final study visit (~4 weeks)]
Вторичные конечные точки (1)
- Local muscle tissue oxygenation during knee extension exercise [Срок оценки: From enrollment to the end of the final study visit (~ 4 weeks)]
Критерии участия
Критерии включения
- Able to understand and communicate in English
- 19-35 years of age
- 65 years of age or older
- All "No" answers on the CSEP Get Active questionnaire or doctors' approval to participate
Критерии исключения
- BMI lower than 18 or greater than 32
- Current use of cigarettes or other nicotine devices
- Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
- Any medical condition impacting the ability to participate in maximal exercise
- Type one or type two diabetes
- Diagnosis of cancer or undergoing cancer treatment in the past 12 months
- Taking blood-thinning medication or the presence of a bleeding disorder
- Drug therapy with any drugs that alter skeletal muscle metabolism (i.e., Metformin, Benzodiazepines)
- Lowest calculated exercise testing load is less than the lightest weight able to be provided by the lab gymnasium equipment
- In the past six months, completing more than 300 minutes of moderate physical activity or 150 minutes of vigorous physical activity per week
- In the past six months, completing less than 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Одна группа
- Маскирование
- Открытое
- Основная цель
- Фундаментальное исследование
Центры проведения
Канада · 1 центр
- Chan Gunn Pavilion — Vancouver
Идентификаторы
NCT: NCT07090603 · H25-01532