Sedentary Activities and Passive-to-Intense Effects on Neuro-Cognitive States

Обзор

Prolonged sedentary behavior is linked to poorer metabolic health, yet its effect on cognitive load and brain function remains unclear. Evidence indicates that "mentally active" sedentary tasks (e.g., reading) may support cognition, whereas "mentally passive" tasks (e.g., scrolling social media) may impair it. The cognitive demands associated with these behaviors across the general population are still poorly defined. This project will compare the acute neurophysiological and perceptual responses elicited by mentally active versus passive sedentary tasks across various age groups and in individuals with specific health conditions (i.e., obesity), clarifying how these behaviors differ in the cognitive load they impose. Neuro-cognitive, physiological, and perceptual responses will be assessed with a multimodal battery that includes portable electroencephalography combined with functional near-infrared spectroscopy (EEG + fNIRS; MUSE), eye-tracking (Pupil Core), alertness and visual fatigue via critical flicker fusion testing (CFFT; Lafayette Instrument), autonomic balance through heart-rate variability (HRV) recorded with a Polar H10 monitor, and the self-reported cognitive load assessed using the NASA Task Load Index (NASA-TLX). We hypothesise that mentally passive sedentary activities will elicit a lower cognitive load than mentally active tasks. By comparing different age groups and health conditions within a single protocol, the study will generate an initial set of group-specific data; subsequent independent studies can build on these findings to explore moderation effects in greater depth. Collectively, the results will provide both the theoretical rationale and the empirical evidence needed to sustain the "mentally active" versus "mentally passive" terminology in sedentary-behaviour research, with the ultimate aim of improving mental and cognitive health.

Вмешательства

• Поведенческое Maximum Cognitive Load
  Participants will perform a working memory task (through N-back 1-to-3) to evaluate the upper limit of cognitive demand.
• Поведенческое Mental active/pasive activities
  Participants will engage in 7 activities, presented in a randomly assigned order across two separate days, to assess their impact on cognitive load: 1. playing a videogame (Tetris ®) 2. listening a podcast (including a final question) 3. watching a documentary (including a final question) 4. reading a document extract (including a final question) 5. watch a reality show extract (including a final question) 6. listening music, they like it 7. scrolling their Tik-Tok/Instagram
• Поведенческое Baseline Cognitive Load
  Participants will sit quietly for 5 minutes to establish baseline spontaneous neurophysiological parameters.

Первичные конечные точки

• Electroencephalography-derived cortical activity (EEG) [Срок оценки: Day 1 and 2]
• Hemodynamic Response (fNIRS) [Срок оценки: Day 1 and 2]
• Eye-Tracking Metrics [Срок оценки: Day 1 and 2]
• Heart Rate Variability (HRV) [Срок оценки: Day 1 and 2]
• Critical Flicker Fusion Threshold (Flicker Fusion) [Срок оценки: Day 1 and 2]
• Self-Reported Cognitive Load (NASA-TLX) [Срок оценки: day 2]

Критерии участия

Критерии включения

• Children aged 5 to 17 years, attending school.
• Adults aged 18 and above, without an upper age limit.
• Participants with and without specific health conditions, such as obesity.
• Ability to perform sedentary activities and comprehend instructions.

Критерии исключения

• Severe visual impairments affecting reading or text visualization.
• Use of conventional glasses and history of migraine or epilepsy (due to preventive request for the flicker fusion test)
• Current use of medications that significantly influence cognitive function (unless the health condition being evaluated requires it).
• Other conditions interfering with cognitive or neurophysiological assessments.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Чили · 1 центр

• Pontificia Universidad Católica de Valparaíso — Viña del Mar

Идентификаторы

NCT: NCT07087236 · BIOEPUCV-H 858-2024

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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