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Идёт набор NCT07081282

Precision Stratification for Frailty and Cognitive Decline

Без фазы С лечением Frailty Cognitive Decline

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB), Centre-Based Exercise Health Session.
Кому может быть актуально
Состояния в реестре: Frailty, Cognitive Decline. Базовые параметры: 60 лет — 85 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Сингапур
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Precision Care Pathway Through Frailty and Cognitive Assessment Among Older Adults and Development of Care4Senior App, Intensive Aerobic Resistance Training and Brain Health Program in the Community

Обзор

The Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial aim to test the effectiveness of an exercise, cognitive and lifestyle intervention amongst older adults over a 12-weeks trial period to prevent frailty and promote social bonding.

Подробное описание

In the Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial, participants will use the Care4Seniors 2.0 mobile application, in which physical and cognitive exercises will be provided to participants using this digital technology. Weekly in-person group exercise and cognitive sessions will also be conducted to prevent frailty, promote social bonding, as well as reduce social isolation and loneliness.

In the long term, this new service model has the potential to transform care, contain healthcare cost inflation and increase the efficiency of the lean manpower. It will translate knowledge into practice, resulting in impactful outcomes such as better self-management and healthy longevity. The CIRTAB program will raise the awareness of health behaviour, thus attracting more older adults to engage in preventive health and thus better prepare them for healthy ageing.

Вмешательства

  • Поведенческое Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)
    Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)
  • Поведенческое Centre-Based Exercise Health Session
    Participants will receive one time centre-based exercise health programme each week.

Первичные конечные точки

  • Frailty Status: - Edmonton Frailty Scale - Clinical Frailty Scale - Oral Frailty Index-8 [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Presence of Sarcopenia: - Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC-F) Questionnaire [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Presence of Cognitive Decline: - Montreal Cognitive Assessment - Symbol Digit Modalities Test - Cognitive Predictive Risk Score (developed from previous study) [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Immunological Biomarkers: - C1q (complement component 1q) - IL-6 (Interleukin-6) [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Skeletomuscular Biomarkers: - IGF-1 (Insulin-like Growth Factor-1) - Myostatin [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
Вторичные конечные точки (4)
  • Self-Care Ability - Self-Care of Chronic Illness Inventory (SCCII) [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Physical Activity Level - Global Physical Activity Questionnaire (GPAQ) [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Physical Function - Short Physical Performance Battery (SPPB) [Срок оценки: From enrollment to the end of treatment at 12 weeks.]
  • Intrinsic Capacity - World Health Organization (WHO) Integrated Care for Older People (ICOPE) tool [Срок оценки: From enrollment to the end of treatment at 12 weeks.]

Критерии участия

Критерии включения

  • Older Adults Aged 60 to 85 years old
  • Living in the community
  • Formally diagnosed with at least one chronic disease
  • Able to communicate in either English or Mandarin

Критерии исключения

  • Severe vision or hearing impairment
  • Diagnosed with severe cognitive impairment (e.g. dementia)
  • Diagnosed with severe psychiatric disorders (e.g. psychotic disorders, major depressive disorder)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Открытое
Основная цель
Профилактика

Центры проведения

Сингапур · 1 центр
  • Active Ageing Centres Under Changi General Hospital's Community Health Team Cluster (East — Singapore

Идентификаторы

NCT: NCT07081282 · NUS-IRB-2023-526

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗