Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Symptoms

Обзор

The goal of this clinical trial is to learn if a medical-social collaboration model works to reduce depressive symptoms in middle-aged and older adults with depressive symptoms who are waiting for their first psychiatric appointment. Secondary outcomes of the study include reduced anxiety symptoms, reduced loneliness, reduced rumination, reduced self-criticism, improved self-reassurance, improved resilience, improved self-efficacy, improved health-related quality of life, as well as improved quality-adjusted life years, and reduced healthcare service utilisation. Researchers will compare a medical-social collaboration model to a self-management booklet. Participants will: * Receive CBT-based stepped-care interventions through the medical-social collaboration model or a self-management booklet. * Complete a survey about their mental health and service use every three months until their first psychiatric appointment.

Вмешательства

• Поведенческое Cognitive behavioural therapy-based stepped-care intervention
  After initial clinical assessment, participants will be offered interventions based on their depressive symptom severity (Patient Health Questionnaire-9-item \[PHQ-9\]). Mild symptoms (PHQ-9=5-9): 6 weekly low intensity CBT-based group intervention sessions led by trained clinical social workers, with 2 booster sessions as necessary. Moderate symptoms (PHQ-9=10-14): 6 weekly high intensity CBT-based group intervention sessions led by trained clinical social workers, with 2 booster sessions as ne
• Другое Self-management booklet
  The booklet incorporates components of behavioural activation, which encourages participants to engage in meaningful activities in daily life to change their mood. Trained research assistants will regularly check in with the participants to monitor their depressive symptoms.

Первичные конечные точки

• Changes in Depressive Symptoms [Срок оценки: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months]

Вторичные конечные точки (4)

• Changes in Anxiety Symptoms [Срок оценки: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months]
• Changes in Loneliness [Срок оценки: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months]
• Changes in Health Service Use [Срок оценки: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months]
• Changes in Health-Related Quality of Life [Срок оценки: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months]

Критерии участия

Критерии включения

• Currently awaiting psychiatric services provided by the Hospital Authority
• Have depressive symptoms of at least mild severity
• Able to provide informed consent

Критерии исключения

• A known history of autism spectrum disorder, intellectual disability, schizophrenia-spectrum disorder, bipolar disorder, Parkinson's disease, or dementia
• Imminent suicidal risk (temporary exclusion)
• Communication difficulties that preclude participation

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Лечение

Центры проведения

Гонконг · 1 центр

• The University of Hong Kong — Гонконг

Идентификаторы

NCT: NCT07064551 · UW 24-649

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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