Идёт набор NCT07051967

Post-intensive Care Syndromes in Pregnant Patients With Respiratory Failure and COVID-19 Compared to Non-pregnant Patients With Respiratory Failure and COVID-19

— Наблюдательное COVID-19 Acute Respiratory Distress Syndrome Due to COVID-19 Pregnancy Related

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: Это наблюдательное исследование: исследуемое лечение участникам по протоколу не назначают.
Кому может быть актуально: Состояния в реестре: COVID-19, Acute Respiratory Distress Syndrome Due to COVID-19, Pregnancy Related. Базовые параметры: от 18 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Германия
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

The aim of this study is to characterize patients in the Post-Intensive-Care-Syndrome (PICS) outpatient clinic based on routine data and to evaluate their treatment outcome over the course of their treatment. For this purpose, data sets from approx. 40 patients who were treated in the intensive care unit subsequently evaluated in the PICS outpatient clinic between March 27, 2020, and May 6, 2024, will be analyzed.

Подробное описание

This is a retrospective comparison of approximately 13 pregnant patients and approximately 27 non-pregnant patients who developed respiratory failure (also known as acute respiratory distress syndrome, or ARDS) due to COVID-19 infection. The analysis is based on routine treatment data from the Post-Intensive Care Syndrome (PICS) outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), as well as intensive care treatment data, primarily from the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK). In some cases, additional data were obtained from the Medical Clinic for Nephrology and Internal Intensive Care Medicine (CCM/CVK/CBF), the Medical Clinic specializing in Hepatology and Gastroenterology (CCM/CVK), and the Department of Infectiology, Pulmonology, and Intensive Care Medicine (CCM).

Первичные конечные точки

Impairment in at least one PICS domain (mobility, cognition, and/or mental health) [Срок оценки: 27.03.2020-06.05.2024]

Вторичные конечные точки (12)

Catecholamine therapy [Срок оценки: 27.03.2020-06.05.2024]
Extracorporeal Membrane Oxygenation treatment [Срок оценки: 27.03.2020-06.05.2024]
Need for ventilation during ICU treatment [Срок оценки: 27.03.2020-06.05.2024]
Duration of ventilation during ICU treatment [Срок оценки: 27.03.2020-06.05.2024]
Oxygenation index [Срок оценки: 27.03.2020-06.05.2024]
Severity of illness [Срок оценки: 27.03.2020-06.05.2024]
Incidence of delirium [Срок оценки: 27.03.2020-06.05.2024]
Duration of delirium [Срок оценки: 27.03.2020-06.05.2024]
Sedation Medications [Срок оценки: 27.03.2020-06.05.2024]
Sedation dosage [Срок оценки: 27.03.2020-06.05.2024]
Duration of sedation [Срок оценки: 27.03.2020-06.05.2024]
Depth of sedation [Срок оценки: 27.03.2020-06.05.2024]

Критерии участия

Критерии включения

Age: 18 years and older
Admission to a Charité intensive care unit and follow-up examination by the Post-Intensive-Care-Syndrome (PICS) outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine between March 27, 2020 and May 6, 2024.
COVID-19 infection in temporal assocoation with the intensive care unit admission.
Intensive care unit admission with lung failure or development of lung failure in the course of intensive care unit treatment.
Admission to the intensive care unit with lung failure or development of lung failure during intensive care unit stay.