Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

Официальное название

Comparing the Effectiveness of Traditional Semantic Feature Analysis (SFA) Versus SFA Plus Metacognitive Strategy Training (SFA+MST) for People With Acquired Aphasia

Обзор

The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are: * What are the comparative outcomes in picture naming accuracy and strategy use during picture naming following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia? * What are the comparative outcomes in percent of informative content and rate of informative content during spontaneous speech production following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia? Researchers will compare outcomes between these two treatments to see if SFA+MST yields larger effects in picture naming and spontaneous speech outcomes than traditional SFA. Participants will complete: * 5-7 pre-treatment assessment sessions where they will be asked to name pictures, tell stories/describe pictures, answer questions, and complete questionnaires, * 3 treatment sessions of SFA \*OR\* SFA+MST per week for 8 weeks, for a total of 24 sessions, * 7 weekly probes (i.e., short, intermittent assessments throughout the treatment phase), * 3 post-treatment assessment sessions immediately after treatment ends, where they will complete the same assessment tasks as they did pre-treatment (e.g., naming pictures, telling stories, etc.), * 2 retention assessment sessions, one 30 days and the other 60 days following the final treatment session, where they will be asked to name pictures, tell stories/describe pictures, and describe what they learned during the study.

Вмешательства

• Поведенческое Semantic Feature Analysis (traditional)
  This treatment involves naming pictures of objects, describing the objects' features (e.g., category membership, physical attributes, etc.), and creating sentences using the objects' names. It does not include direct metacognitive strategy training.
• Поведенческое Semantic Feature Analysis + Metacognitive Strategy Training
  This treatment involves metacognitive teaching and practice, naming pictures of objects, describing the objects' features (e.g., category membership, physical attributes, etc), creating sentences using the objects' names, debriefing on overall performance, and discussing recent and future opportunities for strategy implementation in real life.

Первичные конечные точки

• Confrontation naming accuracy [Срок оценки: Change from Baseline through study completion, an average of 6 months]
• Independent word-finding strategy use [Срок оценки: Change from Baseline through study completion, an average of 6 months]

Вторичные конечные точки (2)

• Discourse informativeness [Срок оценки: Change from Baseline through study completion, an average of 6 months]
• Discourse efficiency [Срок оценки: Change from Baseline through study completion, an average of 6 months]

Критерии участия

Критерии включения

• Have aphasia due to a single acute event (e.g., left-hemisphere stroke, traumatic brain injury)
• Be at least six-months post aphasia-onset,
• Be a proficient English speaker,
• Have normal or corrected to normal hearing (i.e., hearing aids) and vision (i.e., eyeglasses),
• Have no history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug/alcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems

Критерии исключения

• A history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug/alcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems,
• Children under the age of 18,
• Adults over the age of 89,
• Uncorrected hearing and vision.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

США · 1 центр

• Teachers College, Columbia University — New York

Публикации

• Nicholas LE, Brookshire RH. A system for quantifying the informativeness and efficiency of the connected speech of adults with aphasia. J Speech Hear Res. 1993 Apr;36(2):338-50. doi: 10.1044/jshr.3602.338. PMID 8487525
• Gravier ML, Dickey MW, Hula WD, Evans WS, Owens RL, Winans-Mitrik RL, Doyle PJ. What Matters in Semantic Feature Analysis: Practice-Related Predictors of Treatment Response in Aphasia. Am J Speech Lang Pathol. 2018 Mar 1;27(1S):438-453. doi: 10.1044/2017_AJSLP-16-0196. PMID 29497754
• Tilton-Bolowsky VE, Brock L, Nunn K, Evans WS, Vallila-Rohter S. Incorporating Metacognitive Strategy Training Into Semantic Treatment Promotes Restitutive and Substitutive Gains in Naming: A Single-Subject Investigation. Am J Speech Lang Pathol. 2023 Sep 11;32(5):1979-2020. doi: 10.1044/2023_AJSLP-22-00230. Epub 2023 Jul 11. PMID 37433115

Идентификаторы

NCT: NCT07036406 · TeachersCCU

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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