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Набор по приглашению NCT07023146

Effects of Different Power Training Intensities in Older Adults

Без фазы С лечением Investigating the Effects of Power Training in the Elderly

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ), low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM]).
Кому может быть актуально
Состояния в реестре: Investigating the Effects of Power Training in the Elderly. Базовые параметры: от 60 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Бразилия
Следующий шаг
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Официальное название

Adaptations Due to Different Intensities of Power Training on Neuromuscular Performance, Muscle Thickness and Functional Capacity in Elderly People: A Randomized Clinical Trial

Обзор

Power (strength × velocity) is a crucial component for maintaining independence during aging. Therefore, investigating interventions aimed at improving this physical capacity is essential for this population. The aim of this study is to examine the effects of power training (PT) performed at low to moderate intensity (PTLM; 40-60% of 1-repetition maximum \[1RM\]) and moderate to high intensity (PTMH; 65-80% of 1RM) on muscle power, kinematic gait parameters, strength, muscle thickness, and functional performance in older adults. Participants will be randomly assigned to perform PTLM and PTMH. Data collection will occur before and after familiarization, as well as at weeks 8 and 16 of the training programs. Participants will undergo a series of tests in the following sequence: 1) muscle thickness and 1RM test; 2) muscle power, maximum voluntary contraction, and rate of force development; 3) functional performance. The primary analyses will be conducted on an intention-to-treat basis, comparing the effects of the interventions and groups over time. Generalized Estimating Equations (GEE) will be used, considering the factors of group (2 levels) and time (3 levels). Paired comparisons will be assessed using the Bonferroni post-hoc test to identify significant differences between groups and time points. All tests will be performed using JASP software (version 0.16.4.0), with statistical significance set at p \< 0.05 for all analyses.

Вмешательства

  • Устройство Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) )
    Power training performed at maximum velocity in the concentric phase with moderate to high intensity
  • Устройство low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
    Power training performed at maximum velocity in the concentric phase with lower to moderate intensity

Первичные конечные точки

  • Muscle Power [Срок оценки: Pre- and post-intervention (16 weeks of training)]
  • Muscle Strength [Срок оценки: Pre- and post-intervention (16 weeks of training)]
  • Rate of Force Development [Срок оценки: Pre- and post-intervention (16 weeks of training)]
Вторичные конечные точки (3)
  • Functional Capacity [Срок оценки: Pre- and post-intervention (16 weeks of training)]
  • Muscle hypertrophy [Срок оценки: Pre- and post-intervention (16 weeks of training)]
  • Cognitive Capacity [Срок оценки: Pre- and post-intervention (16 weeks of training)]

Критерии участия

Критерии включения

  • Age 60 years or older
  • No participation in regular and systematic resistance training in the last three months
  • No absolute or relative contraindications to exercise
  • No musculoskeletal injuries that could interfere with training and assessments

Критерии исключения

  • Use of steroids, nutritional supplements, or ergogenic substances
  • Failure to complete all study phases
  • Failure to complete more than 80% of the training sessions (32 sessions)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Тройное слепое
Основная цель
Профилактика

Центры проведения

Бразилия · 1 центр
  • Universidade Federal do Rio Grande do Sul (UFRGS) — Porto Alegre

Публикации

  • Martinikorena I, Martinez-Ramirez A, Gomez M, Lecumberri P, Casas-Herrero A, Cadore EL, Millor N, Zambom-Ferraresi F, Idoate F, Izquierdo M. Gait Variability Related to Muscle Quality and Muscle Power Output in Frail Nonagenarian Older Adults. J Am Med Dir Assoc. 2016 Feb;17(2):162-7. doi: 10.1016/j.jamda.2015.09.015. Epub 2015 Nov 11. PMID 26577625
  • Mc Dermott EJ, Balshaw TG, Brooke-Wavell K, Maden-Wilkinson TM, Folland JP. Fast and ballistic contractions involve greater neuromuscular power production in older adults during resistance exercise. Eur J Appl Physiol. 2022 Jul;122(7):1639-1655. doi: 10.1007/s00421-022-04947-x. Epub 2022 Apr 16. PMID 35429294
  • Bandeira-Guimaraes M, Blanco-Rambo E, Vieira AF, Saez de Asteasu ML, Pinto RS, Izquierdo M, Cadore EL. Chronic Effects of Different Intensities of Power Training on Neuromuscular Parameters in Older People: A Systematic Review with Meta-analysis. Sports Med Open. 2023 Oct 24;9(1):98. doi: 10.1186/s40798-023-00646-9. PMID 37874417
  • de Vos NJ, Singh NA, Ross DA, Stavrinos TM, Orr R, Fiatarone Singh MA. Optimal load for increasing muscle power during explosive resistance training in older adults. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):638-47. doi: 10.1093/gerona/60.5.638. PMID 15972618

Идентификаторы

NCT: NCT07023146 · 85503024.6.0000.5347

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗