Effect of Cross-linked Hyaluronic Acid Filler Versus Botulinum Toxin Type A (Botox) in Management of Gummy Smile
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Injection of cross linked hyaluronic acid filler.
- Кому может быть актуально
- Состояния в реестре: Gummy Smile Due to Hypermobile Upper Lip. Базовые параметры: 18 лет — 60 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Египет
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Effect of Cross-linked Hyaluronic Acid Filler Versus Botulinum Toxin Type A (Botox) in Management of Gummy Smile: Randomized Controlled Clinical Trial
Обзор
A smile is supposed to express one's feelings and expressions, for that there has been an awakening concern for the appearance of gummy smile. Gummy smile is the appearance of about 2mm or more of the gingiva during smiling. It may affect the quality of life of individuals affecting their self-esteem; patients desire to look good not only while resting but while dynamically expressing themselves too. Variable factors contribute to this gingival display whether skeletal, dental or muscular. Variable treatment modalities are done solely or in adjunction to each other for the treatment of gummy smile including both surgical or nonsurgical procedures.
Подробное описание
In patients not preferring surgical correction of gummy smile, botulinum toxin injection type A can be a helpful solution for reduction of peri-oral muscular hypermobility. A characteristic feature of botulinum toxin is the need for the re-injection in short intervals of time to yield better lasting effects. The use of cross-linked hyaluronic acid dermal fillers when used to myomodulate the peri-oral muscles give more immediate results and reduces the need for re-injection at shorter intervals.
Botulinum toxin type A, a toxin produced by the bacteria Clostridium botulinum, has been widely used in different therapeutic and cosmetic applications in dentistry. Amongst its important applications is the treatment of gummy smile by reducing the hypermobility of the peri-oral muscles through chemical denervation. Botox elicits temporary results and requires re-injection at certain time points. It is a safe, suitable, transient solution for patients not willing to undergo any surgical intervention to manage their gummy smile. Another approach for the non invasive treatment of muscular hypermobility is the injection of cross linked hyaluronic acid filler. Once the filler is injected, it typically occupies space that lessens the muscle movement limiting its hypermobility. Instant Smile enhancement is observed upon injection of cross-linked hyaluronic acid fillers and no need to repeat the injection at closer periods of time. Hyaluronic acid fillers are non-permanent fillers that are degradable by hyaluronidase and cross linking renders them more resistant to enzymatic degradation thus lasting longer.
Вмешательства
- Процедура Injection of cross linked hyaluronic acid filler
Injection of cross linked hyaluronic acid filler
Первичные конечные точки
- Gingival display [Срок оценки: week 2, month 1, month 3, month 6, month 9]
Вторичные конечные точки (3)
- Patient satisfaction [Срок оценки: week 2, month 1, month 3, month 6, month 9]
- Postoperative pain [Срок оценки: week 2, month 1, month 3, month 6, month 9]
- Lip mobility [Срок оценки: week 2, month 1, month 3, month 6, month 9]
Критерии участия
Критерии включения
- Patients with excessive gingival display ranging from 3-8mm due to hypermobile lip.
- Age ranges from 18 years or above.
Критерии исключения
- Excessive gingival display due to other etiological factors.
- Patients allergic to botox or hyaluronic acid fillers.
- Patients with any medical condition that contraindicates botox or hyaluronic acid filler injection.
- Patients previously injected with permanent fillers.
- Pregnancy.
- Breastfeeding females.
- Patients with active inflammatory or infectious disease at intended site of injection.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Тройное слепое
- Основная цель
- Лечение
Центры проведения
Египет · 2 центра
- CairoU — Cairo
- Cairo University — Giza
Идентификаторы
NCT: NCT06952218 · 5699269