Идёт набор NCT06947642

Ultrasound-guided Pectoral Nerve Blocks, Thoracic Erector Spinae Plane Block and Serratus Anterior Plane Block for Breast Surgery

Без фазы С лечением Ultrasound Pectoral Nerve Blocks Thoracic Erector Spinae Plane Block Serratus Anterior Plane Block

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Pectoral nerve block (PECS), Erector spinae plane block (ESP), Serratus anterior plane block (SAP).
Кому может быть актуально: Состояния в реестре: Ultrasound, Pectoral Nerve Blocks, Thoracic Erector Spinae Plane Block, Serratus Anterior Plane Block. Базовые параметры: 21 лет — 65 лет · Женщины.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Египет
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Comparison Between Ultrasound-guided Pectoral Nerve Blocks, Thoracic Erector Spinae Plane Block and Serratus Anterior Plane Block for Breast Surgery: A Prospective Randomized Study

Обзор

The study will compare ultrasound-guided Pectoral nerve block, Erector Spinae Plane block, and Serratus anterior plane block for pain management following elective breast surgeries

Подробное описание

Adequate acute postoperative pain control is important for patients undergoing breast surgery because the pain may be severe and longlasting. Surgical incision at the breast and axillary areas is associated with significant pain, with high incidence of acute pain progressing to chronic pain in 25% to 60% of patients. Post-mastectomy pain managed with opioids often lead to side effects of nausea and vomiting.

Regional anesthetic techniques are used in the current management of pain associated with breast surgeries .They attenuate surgical stress response , intraoperative consumption of opioid, prevent central sensitization and diminish postoperative pain.

The efficacy of fascial plane blocks like pectoral nerve block (PECS), serratus anterior plane block (SAP), and erector spinae plane block (ESP) has been proven in previous studies. These blocks require deposition of local anesthetic in an inter-fascial plane through which peripheral nerves travel.

The Pectoral nerve block relies upon the deposition the local anesthetic at the inter-fascial planes among the pectoralis major, minor, and serratus anterior muscles: it blocks the pectoral, the intercostobrachial, the intercostals III and VI, and the long thoracic nerves.

Erector Spinae Plane block is another interfacial plane block. It involves deposition of local anesthetic between erector spinae muscle and transverse process of T5 vertebrae and targets both dorsal and ventral rami of thoracic spinal nerves.

Serratus anterior plane block involves the injection of local anesthetic in 1 of the 2 fascial planes, superficial and deep to serratus anterior muscle at the level of the fifth rib in midaxillary line. The SAP block targets the lateral cutaneous branches of the thoracic intercostal nerves. The deep SAP block was found to have similar analgesic efficacy and technically easier and safer to perform as compared to the superficial SAP block.

Вмешательства

Препарат Pectoral nerve block (PECS)
Patients will receive pectoral nerve block (PECS).
Препарат Erector spinae plane block (ESP)
Patients will receive erector spinae plane block (ESP).
Препарат Serratus anterior plane block (SAP)
Patients will receive serratus anterior plane block (SAP).

Первичные конечные точки

Total morphine consumption [Срок оценки: 24 hours postoperatively]

Вторичные конечные точки (7)

Time to the 1st rescue analgesia [Срок оценки: 24 hours postoperatively]
Intraoperative fentanyl consumption [Срок оценки: Intraoperatively]
Pain degree [Срок оценки: 24 hours postoperatively]
Mean arterial blood pressure [Срок оценки: Till the end of surgery (Up to 24hours)]
Heart rate [Срок оценки: Till the end of surgery (Up to 24hours)]
Patient satisfaction [Срок оценки: 24 hours Postoperatively]
Adverse effects [Срок оценки: 24 hours Postoperatively]

Критерии участия

Критерии включения

Age from 21 to 65 years old female, American Society of Anesthesiologists (ASA) physical status I or II, who will undergo breast surgeries under general anesthesia.