Dairy vs Plant-based Beverages for Improving Bone Health During Exercise

Официальное название

Dairy Versus Plant-based Beverages Combined With Resistance-training for Improving Bone Health

Обзор

This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.

Подробное описание

The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.

Вмешательства

• Пищевая добавка Nutritional supplementation during a 12 month resistance training program
  1% chocolate milk
• Пищевая добавка Nutritional supplementation during a 12 month resistance training program
  pea-based beverage
• Пищевая добавка Nutritional supplementation during a 12 month resistance training program
  almond-based beverage

Первичные конечные точки

• Change in section modulus at the hip (cm to the power of 3) [Срок оценки: 12 months]

Вторичные конечные точки (12)

• Change in lumbar spine bone mineral density (g/cm-squared) [Срок оценки: 12 months]
• Change in hip bone mineral density (g/cm-squared) [Срок оценки: 12 months]
• Change in cross-sectional area at the hip (cm-squared) [Срок оценки: 12 months]
• Change in cortical thickness at the hip (cm) [Срок оценки: 12 months]
• Change in buckling ratio at the hip (no units) [Срок оценки: 12 months]
• Change in bench press strength (kg) [Срок оценки: 6 and 12 months]
• Change in knee extension strength (kg) [Срок оценки: 6 and 12 months]
• Change in lean tissue mass (kg) [Срок оценки: 12 months]
• Change in fat mass (kg) [Срок оценки: 12 months]
• change in 30 second sit to stand (number of repetitions) [Срок оценки: 6 and 12 months]
• Change in walking speed (m/s) [Срок оценки: 6 and 12 months]
• Change in timed up and go performance (s) [Срок оценки: 6 and 12 months]

Критерии участия

Критерии включения

• Women need to be postmenopausal (no age limit)
• Men need to be 50y or older

Критерии исключения

• Taking medications that might affect bone
• Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
• Planning 6 weeks of travel during the 12 month intervention period
• Planning major surgery during the 12 month intervention period
• Already strength training greater than 2 days per week for 30 minutes or longer per session
• Allergies to ingredients in the beverages

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Тройное слепое

Основная цель

Профилактика

Центры проведения

Канада · 1 центр

• College of Kinesiology University of Saskatchewan — Saskatoon

Идентификаторы

NCT: NCT06946316 · 361218

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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