Different Injection Speed on Local Anaesthetic Spread of ESPB

Senventy-four patients were selected to undergo CT guided puncture localization of lung nodules under local anesthesia, and the patients were divided into groups using a computer-generated random number in a ratio of 1:1. To ensure objectivity, a nurse who was not involved in the study prepared a sealed opaque envelope containing grouping information. Patients were randomly divided into two groups: control group (group C, 37 patients), and experimental group (group S, 37 patients). All patients underwent ultrasound guided ESPB before CT-guided nodule localization. Ultrasound guided ESPB method: Using a high-frequency linear probe (5-13 MHz, Sonosite, USA), the probe is placed parallel to the spine on the surface of the transverse process tip of the seventh thoracic vertebrae. Under ultrasound, the transverse process and spinal muscles are clearly exposed. Then, a long beveled needle is used, and inserted from the cephalad to caudal with in-plane technique. After the needle tip reaches between the transverse process and erector spinae muscles, 2ml saline is injected using water separation technique to confirm the position of the needle tip, then injecting 30ml local anesthetic solution (0.75% ropivacaine 15ml+iohexol 15ml). In the control group, the injection is administered at a rate of 30 ml within 180 seconds. In the experimental group, the injection is delivered at a faster rate of 30 ml withinr 30 seconds. After 30 minutes of block completion, CT scan and puncture localization were performed, following with 3D reconstruction. The primary outcome was mixture spread to the paravertebral space.The second outcomes were as follow: 1.spread to the intercostal space. 2. spread to the epidural space 3.spread to the neural foramina 4. cranio-caudal spread

• Diffusion of local anesthetic into intercostal space [Срок оценки: 30 minutes after completion of the block]
• Diffusion of local anesthetic into the epidural space [Срок оценки: 30 minutes after completion of the block]
• Diffusion of local anesthetic into the neural foramina [Срок оценки: 30 minutes after completion of the block]
• Cephalocaudal spread of local anesthetic [Срок оценки: 30 minutes after completion of the block]
• Loss to Cold Sensation of Skin [Срок оценки: 30 minutes after block]
• NRS (Numeric Rating Scales) Score [Срок оценки: 1 hour after CT-guided nodule localization]
• Hemodynamic profile [Срок оценки: Heart rate changes before blockade, 5minute after blockade, 10 minute after blockade, 20minute after blockade, 30minute after blockade]
• Hemodynamic profile [Срок оценки: Mean arterial pressure changes before blockade, 5minute after blockade, 10 minute after blockade, 20minute after blockade, 30minute after blockade]