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Идёт набор NCT06932679

Perception of Affordances and Obstacle Crossing in People With Parkinson's Disease and Healthy Adults

— Наблюдательное Parkinson's Disease (PD)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Assessment of Gait and Visual Exploration.
Кому может быть актуально
Состояния в реестре: Parkinson's Disease (PD). Базовые параметры: 20 лет — 80 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Израиль
Следующий шаг
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Официальное название

Affordances and Impairments: A Paradigm for Understanding Obstacle Crossing in Parkinson's Disease

Обзор

This study aims to explore how young adults, older adults and people with Parkinson's disease (PwP), perceive their abilty to cross obstacles while walking, and how this perception is related to their actual performance of obstacle crossing and disease-related motor and cognitive impairments. The study will explore this percepeption and the actual performance in different walking environments(floor, synthetic grass turf). Understanding how people perceive obstacles may help improve rehabilitation methods and reduce the risk of falls. The study will take place at the Motor Performance Laboratory, University of Haifa, and will include walking tasks, eye-tracking measurements, and motor and cognitive assessments.

Подробное описание

This study investigates the role of affordance perception - the ability to perceive opportunities for action - during obstacle crossing in people with Parkinson's disease (PwP). Falls are highly prevalent in PwP, often resulting from tripping over obstacles. While previous research has mainly focused on gait impairments, this study uniquely examines the perceptual stage that precedes movement and the association between perception, cognition, and motor performance.

Participants will include 60 PwP and 120 healthy adults (60 older adults and 60 young adults). All participants will perform walking tasks involving obstacle crossing under different environmental conditions (e.g., different obstacle heights and surfaces). Prior to walking, participants will judge whether they can safely cross the obstacle. Eye-tracking glasses will measure visual exploration patterns to assess how participants scan the environment. Additionally, walking variables such as speed and step length, will be recorded using wearable sensors.

The study will explore:

1. Differences in affordance perception between PwP and healthy adults. 2. Associations between motor and cognitive impairments and affordance perception in PwP. 3. How affordance perception relates to gait performance during obstacle crossing.

Results from this study may help to develop new intervention strategies aimed at improving safe walking and obstacle negotiation in PwP.

Вмешательства

  • Другое Assessment of Gait and Visual Exploration
    Participants will perform walking tasks involving obstacle crossing while their gait and visual exploration patterns are recorded using wearable sensors and eye-tracking glasses. This is a non-invasive observational study with no therapeutic intervention.

Первичные конечные точки

  • Affordance Perception Accuracy [Срок оценки: During single laboratory session (about 3 hours)]
  • Affordances measured by gaze behavior [Срок оценки: During a single laboratory session (approximately 3 hours)]
Вторичные конечные точки (5)
  • Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) [Срок оценки: During a single laboratory session (approximately 3 hours)]
  • Walking Speed [Срок оценки: During a single laboratory session (approximately 3 hours)]
  • Step Length [Срок оценки: During a single laboratory session (approximately 3 hours)]
  • Levodopa Equivalent Daily Dose (LEDD) [Срок оценки: During a single laboratory session (approximately 3 hours)]
  • Cognitive Performance - Stroop Test (NeuroTrax Cognitive Battery) [Срок оценки: During a single laboratory session (approximately 3 hours)]

Критерии участия

Критерии включения

  • Participants aged 20 to 80 years.
  • Ability to walk independently outdoors without assistive devices.
  • For Parkinson's Disease (PD) group: Diagnosis of PD confirmed by medical records.
  • For healthy control groups: No neurological or orthopedic conditions affecting gait.

Критерии исключения

  • Feezing of gait (for PD group only), based on a score greater than 0 on the Freezing of Gait Questionnaire.
  • Severe visual impairment that cannot be corrected with glasses or lenses.
  • Cognitive impairment, defined as a score below 18 on the telephone-based Mini-Mental State Examination (MMSE).
  • Any orthopedic condition, pain, or other medical condition that may affect walking, based on self-report.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Модель наблюдения
Случай-контроль

Центры проведения

Израиль · 1 центр
  • University of Haifa, Motor Performance Laboratory — Haifa

Идентификаторы

NCT: NCT06932679 · 1561/25

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗