To Evaluate Transport Safety Between Different Scanning Methods for Patients in the Intensive Care Unit (ICU)

Официальное название

Comparative Safety Analysis: PET vs. CT Scans During Intensive Care Admission

Обзор

The goal of this study is to assess how safe it is for critically ill patients in the Intensive Care Unit (ICU) to undergo a PET scan. A PET scan is a type of medical imaging used to help determine why a patient is sick. It is similar to a CT scan but involves a small amount of radioactivity to highlight areas of concern in the body. For a PET scan, patients need to be transported from the ICU to the scanning room, which can be risky because ICU patients are often very fragile. After a patient gets the PET scan injection, their body gives off a small amount of radiation for a short time. Because of this, doctors and nurses have to keep some distance to protect themselves. This means they keep an eye out for the patient from a bit further away than normal. This makes the procedure slightly riskier, especially for very sick patients. This study aims to answer the question: Is getting a PET scan riskier for ICU patients than a regular CT scan? All patients in this study will continue to receive their usual critical care. Researchers will closely monitor the scanning process to evaluate its safety. PET scans are already widely used to detect cancer, but new advancements may allow us to use them more often to diagnose infections. Before this can become routine practice, we need to ensure that PET scanning is just as safe as other commonly used imaging techniques. This study will assess all ICU patients undergoing a PET scan-regardless of the reason for the scan-to determine how safe the procedure is in critically ill individuals.

Первичные конечные точки

• Adverse Events [Срок оценки: Measured during the transport phase and 4 hours after return to the Intensive Care Unit.]

Вторичные конечные точки (3)

• Employee dosimetry [Срок оценки: Transport and the hands-off time after scan (i.e. 4h in case of [18]FDG PET scanning)]
• Dietary Adjustment [Срок оценки: 24-48 hours before scan procedure and until 24 hours after cessation of the diet.]
• Kidney failure (KDIGO) [Срок оценки: Day of the scan and up to 3 days after the scan to evaluate the effect on kidney function (i.e. creatinine and urine creatinine will be measured 4 times and evaluated for significant alterations after the application of iodine contrast (if given))]

Критерии участия

Критерии включения

• Patients receiving PET/CT during ICU admission (any indication)
• Patients undergoing CT Thorax/Abdomen (matched cohort)

Критерии исключения

• CT-scan for any acute indication (acute danger to vital parameters).
• CT-Cerebrum
• Registrion in the dutch Objection to medical research registry.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Нидерланды · 1 центр

• University Medical Center Groningen — Groningen

Публикации

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Идентификаторы

NCT: NCT06912464 · 20649

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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