Идёт набор NCT06886906

Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain

Без фазы С лечением Older People Pain

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Intermittent light walking, uninterrupted sitting.
Кому может быть актуально: Состояния в реестре: Older People, Pain. Базовые параметры: 55 лет — 85 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: США
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

The purpose of this research study is to evaluate the effect of brief bouts of intermittent walking on bodily pain, pain during movement, and how the body adapts to musculoskeletal pain in older adults.

Подробное описание

The purpose of this study is to determine whether exposure to acute sitting compared to sitting interrupted with brief bouts of light intensity walking exerts short term effects on resting pain, endogenous pain modulation measured via quantitative sensory testing (QST), and movement-evoked pain (MEP) in older adults. Participants will be asked to complete two study sessions, with the first study session lasting 3 hours and the second study session lasting 2.5 hours. All sessions will take place in the National Institute of Sport Fitness, where the Physical Activity and Pain laboratory is located. The first session will include the following procedures in the following order: informed consent process, healthy history for screening purposes, quantitative sensory testing (QST), 6-minute walk test, completion of questionnaires, QST, experimental conditions of either 1 hour of sitting or 1 hour of sitting with bouts of light intensity walking, QST, and the 30-second chair stand test. Session 2 will take place at least 7 days after session 1 and will be identical except for the informed consent and screening will be replaced by questionnaires and the experimental condition will consist of the one not performed in session 1. Participants will be asked to take their medications at the same time prior to each study visit and the investigators will assess medications taken the day of each visit prior to the visit.

Вмешательства

Поведенческое Intermittent light walking
The participant will remain seated throughout the 1 hour experimental period. During this 1-hour period, participants will complete six bouts of 2.5-minutes of light intensity walking. Overall, the bouts will occur on six occasions, providing a total of 15 minutes of light intensity activity.
Поведенческое uninterrupted sitting
The participant will remain seated throughout the experimental period and will be instructed to minimize excessive movement, only rising from the chair to void. This experimental condition is designed to mimic prolonged uninterrupted sedentary behavior.

Первичные конечные точки

Mechanical Temporal Summation of Pain (TS) [Срок оценки: Pre and post the 1-hour experimental conditions]
Conditioned Pain Modulation [Срок оценки: Pre and post the 1-hour experimental conditions]
Movement-evoked pain during the 30-second chair stand test [Срок оценки: Will be administered immediately after the 1-hour experimental conditions.]

Критерии участия

Критерии включения

Community-dwelling men and women
Answer yes to the following question: Have you experienced any musculoskeletal pain (pain affecting joints, bones, ligaments, tendons or muscles) in the past month?

Критерии исключения

Cardiovascular issues such as uncontrolled blood pressure over 150/99 mmHg, heart failure, or history of acute myocardial infarction;
Angina in the last month (squeezing, pressure, heaviness, tightness, or pain in chest)
Serious systemic disease or condition (e.g., severe osteoarthritis, injury) that restricts normal daily activities
Neurological disease (e.g., Parkinson's Disease, multiple sclerosis, epilepsy)
Serious psychiatric conditions (schizophrenia, bipolar disorder) or hospitalization within the preceding year for psychiatric illness
Known peripheral neuropathy
Chronic opioid use (defined as ≥ 90 days)
Unable to walk for 6 minutes without assistive devices

Session exclusion criteria: