Heart Evaluation of Acute Ischemic Stroke With Reperfusion Therapy
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: observational only- no intervention.
- Кому может быть актуально
- Состояния в реестре: Acute Ischemic Stroke. Базовые параметры: от 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy (HEART) is a single-center observational registry evaluating the heart of patients hospitalized for acute ischemic stroke with reperfusion therapy. This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.
Подробное описание
There is growing evidence pointing to close interactions between acute ischemic stroke (AIS) and heart diseases. Heart diseases may lead to AIS (heart-to-brain interactions), with many cardiac conditions have been proposed as potential sources of cerebral embolism, and studies have also shown that AIS can induce cardiac injury (brain-to-heart interactions), namely Stroke-Heart Syndrome. In addition, due to the commonly shared risk factors, AIS patients had a significantly higher frequency of coexisting prior known or unknown coronary heart disease (brain-and-heart interactions). These heart problems not only add complexity to the etiological diagnosis but also account for a great proportionate mortality in AIS patients with reperfusion therapy, which is the most effective treatment method for AIS. The interconnected and coexisting properties of AIS and heart diseases requires a comprehensive scheme to evaluate, prevent, and treat patients.
Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy (HEART) is a single-center observational registry evaluating the heart of patients hospitalized for acute ischemic stroke with reperfusion therapy.
This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.
The clinical, laboratory and imaging information will be collected at the baseline. During an estimated 3-year follow-up, the diagnostic or monitoring procedures, treatment, functional status and new vascular events will be recorded by web-based patients' self-reports, investigators' regular telephone visits.
Вмешательства
- Другое observational only- no intervention
observational only- no intervention
Первичные конечные точки
- Rate of Major Adverse Cardiovascular Events [Срок оценки: 1 year]
Вторичные конечные точки (11)
- Rate of Major Adverse Cardiovascular Events [Срок оценки: 90 days]
- Functional Outcome [Срок оценки: 90 days]
- Rate of Ischemic Stroke [Срок оценки: 1 year]
- Rate of Acute Coronary Syndrome [Срок оценки: 1 year]
- Rate of Cardiovascular Mortality [Срок оценки: 1 year]
- Time to First Major Adverse Cardiovascular Event [Срок оценки: 3 years]
- Time to First Ischemic Stroke [Срок оценки: 3 years]
- Rate of Major Adverse Cardiovascular Events [Срок оценки: 3 years]
- Rate of Ischemic Stroke [Срок оценки: 3 years]
- Rate of Acute Coronary Syndrome [Срок оценки: 3 years]
- Rate of Cardiovascular Mortality [Срок оценки: 3 years]
Критерии участия
Критерии включения
- Written informed consent by patient
- Age ≥ 18 years
- Acute ischemic stroke (with matching brain lesion on MR imaging)
- Enrolment within 24 h after onset of stroke-related symptoms.
Критерии исключения
- Pregnancy and / or breast-feeding.
- Participation in an interventional study.
- Patients refuse to participate in the research.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- The first affiliated hospital of soochow university — Сучжоу
Идентификаторы
NCT: NCT06882577 · 2025PJ160