High-intensity Functional Training on Functional and Cognitive Performance in People with Parkinson's Disease.

Официальное название

Effectiveness of a High-intensity Functional Training (HIFT) Program on Functional and Cognitive Performance in People with Parkinson's Disease.

Обзор

Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.

Подробное описание

The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease.

Overall objective:

\- To assess whether the HIFT training program is associated with significant improvements in functional and cognitive capacity compared to conventional strength, balance and cognition programs in Parkinson's patients.

Secondary objectives:

1. To assess whether the HIFT program improves the quality of life in patients with PD. 2. To study whether the HIFT program reduces the degree of dependency of patients with PD. 3. To determine if the HIFT program improves physical performance in patients with PD 4. To assess whether the HIFT program reduces the risk of falls in patients with PD. 5. To investigate whether the HIFT program improves balance in patients with PD. 6. To determine if the HIFT program improves functional capacity in patients with PD. 7. To study whether the HIFT program improves cognitive function in patients with PD

Вмешательства

• Другое high intensity functional training
  The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetit

Первичные конечные точки

• Short physical performance battery (SSPB) [Срок оценки: 10 minutes]
• Trail Making Test A y B [Срок оценки: 15 minutes]

Вторичные конечные точки (5)

• SF-12 Health Questionnaire [Срок оценки: 10 minutes]
• Barthel index [Срок оценки: 10 minutes]
• fall risk assessment scale [Срок оценки: 5 minutes]
• 2-minute walk test (2-MWT) [Срок оценки: 5 minutes]
• Mini Mental State Examination [Срок оценки: 20 minutes]

Критерии участия

Критерии включения

• Diagnosis of Parkinson's disease.
• Stage I or II (Hoehn - Yahr Scale).
• Age between 45 and 80 years.
• Independent ambulation for 10 consecutive minutes.
• Regular physical exercise.

Критерии исключения

• Medical contraindication for physical activity, deafness or limited hearing and very low vision or blind.
• Vestibular disorders that compromise balance.
• Psychotic or severe cognitive disorder.
• Decompensation or changes in medication.
• Surgical intervention in the last 6 months.
• Sedentary persons

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Одна группа

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Испания · 1 центр

• University of Valencia — Valencia

Идентификаторы

NCT: NCT06879821 · 2022_TesisIVargas_UV

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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