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Набор скоро начнётся NCT06877000

Vitiligo Severity, Quality of Life, Work Productivity and Activity Impairment

— Наблюдательное Vitiligo

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: VITIQOL questionnaire.
Кому может быть актуально
Состояния в реестре: Vitiligo. Базовые параметры: 18 лет — 60 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Vitiligo Severity, Quality of Life, Work Productivity and Activity Impairment Among Patients in Upper Egypt

Обзор

translate and validate the vitiligo specific quality of life (VITIQOL) questionnaire to Arabic language. evaluate the effect of vitiligo on patient quality of life using vitiligo specific quality of life questionnaire (VitiQoL). measure the impact of vitiligo on work productivity using work productivity and activity impairment questionnaire (WPAI) and general self efficacy scale (GSE) . analyze how disease severity and location influence patients quality of life and work pro

Подробное описание

Vitiligo is a common disorder of depigmentation caused by the progressive destruction of melanocytes that affect the skin, hair and mucous membranes, clinically presenting as depigmented macules and leukotrichia.

Vitiligo was historically regarded as a cosmetic disorder; however, it is an immune disease as it affects patient well-being . It affects approximately 0.5-1% of the global population. A Study reported a prevalence of 1.2% in the Egyptian population.

Vitiligo is asymptomatic disease, so its effect on quality of life is much more related to psychological problems, such as lack of self-confidence unpleasant body images unsuccessful social relationships, and lower quality of marital relations, than the exclusive physical issues. It has been shown that patients with vitiligo are at risk of higher social discrimination and stigma Lesions that are more severe, on the face, or covering a greater BSA are more often associated with poorer outcomes and activity impairment.

Recently a study conducted in Egypt in 2023 noted that more than half of studied sample had low level of self-esteem and quality of life. While more than half of studied sample had moderate negative body image. Also, half of studied sample had moderate level of social problems .

limited studies have been conducted in Upper Egypt which assess life quality of patients with vitiligo and but those Studies employed non-specific tools like Dermatology Life Quality Index (DLQI).

Lilly et al have developed a reliable tool with high internal consistency named as Vitiligo specific Quality of life questionnaire(VITIQOL) that consists of 16 questions comprising of demographic and clinical parameters of the patients.

Also the work productivity and activity impairment among vitiligo patients in Egypt have not been assessed before .

Вмешательства

  • Другое VITIQOL questionnaire
    16 questions questionnaire measure effect of vitiligo on quality of life

Первичные конечные точки

  • Arabic validated version of vitiligo specific quality of life instrument VITIQOL [Срок оценки: Baseline]
  • Patients with severe vitiligo which will be measured by vitiligo area scoring index VASI score , will have lower quality-of-life on vitiligo specific quality of life instrument which have a score ranges from 0 to 90 [Срок оценки: Baseline]
  • patients with more severe vitiligo have low work productivity and more activity impairment [Срок оценки: Baseline]

Критерии участия

Критерии включения

  • Adults > 18 years and less than 60 years old diagnosed with vitiligo by a physician Patients willing to complete the survey questionnaires Patients who can speak Arabic

Критерии исключения

  • Patients with other major skin disease affecting QOL . Patient with chronic diseases as diabetes mellitus and hypertension Not working patients

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Дизайн исследования

Модель наблюдения
Случай-контроль

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

  • Attallah, D. A., Abdullah, M. A. A., & Abou-Taleb, D. A. E. (2022). Effect of treatment on quality of life in Egyptian vitiligo patients using the Arabic version of Dermatology Life Quality Index. Journal of Current Medical Research and Practice, 7(2), 163-166.
  • Lilly E, Lu PD, Borovicka JH, Victorson D, Kwasny MJ, West DP, Kundu RV. Development and validation of a vitiligo-specific quality-of-life instrument (VitiQoL). J Am Acad Dermatol. 2013 Jul;69(1):e11-8. doi: 10.1016/j.jaad.2012.01.038. Epub 2012 Feb 25. PMID 22365883
  • Rosmarin D, Soliman AM, Piercy J, Marwaha S, Anderson P, Camp HS. Health-Related Quality of Life Burden Among Adults with Vitiligo: Relationship to Disease Severity and Disease Location. Dermatol Ther (Heidelb). 2024 Jun;14(6):1633-1647. doi: 10.1007/s13555-024-01187-z. Epub 2024 Jun 2. PMID 38824482

Идентификаторы

NCT: NCT06877000 · Vitiligo quality of life

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗