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Идёт набор NCT06868862

Acute Effects of Isoenergetic HIIE Vs. MICE on Key Parameters of Fat Mass Loss in Young Females with Overweight or Obesity

Без фазы С лечением Overweight and Obese Adults High Intensity Interval Exercise (HIIE)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Exercise.
Кому может быть актуально
Состояния в реестре: Overweight and Obese Adults, High Intensity Interval Exercise (HIIE). Базовые параметры: 20 лет — 45 лет · Женщины.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Бразилия
Следующий шаг
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Официальное название

Acute Physiological Responses to Isoenergetic High-Intensity Interval Vs. Moderate-Intensity Continuous Exercise in Overweight or Obese Young Females: Focus on Catecholamines, Oxygen Consumption, Lipid Utilization, and Appetite Regulation

Обзор

Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear. This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.

Вмешательства

  • Другое Exercise
    Two Exercise Modalities: HIIE and MICE

Первичные конечные точки

  • Oxygen consumption during exercise and the recovery period [Срок оценки: Measurement at rest for 20 minutes, then during warm-up for 10 minutes, then during exercise for 20 minutes and finally during 2 hours after the end of the exercise.]
Вторичные конечные точки (4)
  • Lipid before and after the exercise. [Срок оценки: Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise.]
  • Carbohydrate before and after the exercise. [Срок оценки: Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise.]
  • Catecholamines [Срок оценки: 5 collections: before exercise started, at the end of exercise (exercise duration is 20-35 minutes), at 30 minutes, 60 minutes and 120 minutes after the end of exercise]
  • Energy intakes 24 hours after the exercise [Срок оценки: 24 hours post exercise]

Критерии участия

Критерии включения

  • women with overwieght or obesity (BMI: 25-35 kg/m²)

Критерии исключения

  • contraceptive use
  • menopause
  • irregular menstrual cycle
  • medical contraindications to intense physical activity,
  • painful joints,
  • taking ß-blocker

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Нерандомизированное
Модель
Перекрёстный дизайн
Маскирование
Простое слепое
Основная цель
Профилактика

Центры проведения

Бразилия · 1 центр
  • Laboratório de Fisiologia e Metabolismo Aplicados à Educação Física — São Paulo

Публикации

  • Dupuit M, Rance M, Morel C, Bouillon P, Pereira B, Bonnet A, Maillard F, Duclos M, Boisseau N. Moderate-Intensity Continuous Training or High-Intensity Interval Training with or without Resistance Training for Altering Body Composition in Postmenopausal Women. Med Sci Sports Exerc. 2020 Mar;52(3):736-745. doi: 10.1249/MSS.0000000000002162. PMID 31524825
  • Dupuit M, Boscaro A, Bonnet A, Bouillon P, Bruno P, Morel C, Rance M, Boisseau N. Acute metabolic responses after continuous or interval exercise in post-menopausal women with overweight or obesity. Scand J Med Sci Sports. 2020 Dec;30(12):2352-2363. doi: 10.1111/sms.13814. Epub 2020 Sep 18. PMID 32881054
  • Cunha FA, Midgley AW, McNaughton LR, Farinatti PT. Effect of continuous and intermittent bouts of isocaloric cycling and running exercise on excess postexercise oxygen consumption. J Sci Med Sport. 2016 Feb;19(2):187-92. doi: 10.1016/j.jsams.2015.02.004. Epub 2015 Feb 23. PMID 25747467

Идентификаторы

NCT: NCT06868862 · CAAE: 79561024.4.0000.9487

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗