Graded Activity Training and Task- Oriented Training on Post-Stroke Fatigue

Официальное название

Effects Of Graded Activity Training and Task-Oriented Training on Fatigue in Post-Stroke Patients

Обзор

The aim of this randomized controlled trial is to determine the effects of Graded Activity Training and Task Oriented Training on Fatigue in Post-Stroke Patients. Until now there is very limited work found on fatigue so this will increase quality of life in stroke patients and potentially reduce burden on healthcare system.

Подробное описание

Post stroke fatigue (PSF) is one of the most common outcomes of stroke. PSF is defined as "overwhelming feeling of exhaustion or tiredness" as a result of stroke PSF is an undesirable outcome by which patient's ability in study participation, adherence to medication and effectiveness of rehabilitation decrease which is unrelated to exertion, and does not typically improve with rest. Prevalence rate of PSF ranges between 25% and 85% One out of two stroke survivors experience post-stroke fatigue. The relationship between physical deconditioning and fatigue is bidirectional there was a negative relationship between fatigue and aerobic fitness in chronic stroke. PSF may arise from physical deconditioning (physical fatigue). Therefore, improving physical endurance through physical activity training could potentially reduce fatigue complaints.

The rationale of this study is to determine how task-oriented training and graded activity training effect stroke patient's levels of fatigue and to develop an improved fatigue management intervention protocol. This study will also determine effects of how both interventions affect Mobility and Gait. By doing so, we can identify a more effective PSF intervention plan, which will help reduce the burden on the healthcare system and will lessen strain on caregivers and in turn enhance patient quality of life.

Вмешательства

• Другое Graded Activity Training
  4 types of progressive activities of 2 hour session two times/week with resting periods of 30 mins. Activities consist of treadmill walk ,walk on floor, core muscles exercises ,home tasks . To ensure the proper heart rate and loads during the exercises, measurements of individual heart rate and muscle strength are taken during the first session (baseline) with HR Tracking portable device and also during the session to continuously monitor HR of the Patient. To withdraw or adjust the training in
• Другое Task-Oriented Training
  4 task oriented physical fitness activities which include walk on floor, walk on inclined surface using treadmill ,sit to stand , stair climbing and descending for duration of 2 hour session with frequent breaks. Each treatment session began with 10 minutes of warm-up exercise, which consisted of passive stretching of the calf muscles, hamstring, and hip adductors. The level of difficulty and frequency for each task were gradually increased during the 6 weeks with the patients consent.10 minutes

Первичные конечные точки

• Fatigue Assessment scale (FAS) [Срок оценки: 6 weeks]

Вторичные конечные точки (2)

• Timed Up and go test(Mobility) [Срок оценки: 6 weeks]
• Dynamic gait index (Gait) [Срок оценки: 6 weeks]

Критерии участия

Критерии включения

• Both male and female of age 40 to 60 years.
• Patient with both ischemic or hemorrhagic stroke.
• Patient with both right and left hemiplegia.
• Checklist Individual (CIS-F) fatigue score of 40 or more.
• Patients who had sustained a stroke more than 4 months before recruitment.
• Patients who can independently walk for 10 meters (about 33 feets)

Критерии исключения

• Patients with severe comorbid health conditions (such as cardiac diseases, pulmonary diseases like COPD, Orthopedic Conditions Arthritis, joint replacements).
• Patients with uncontrolled diabetes, hypertension, Depression and Anxiety.
• Patients who are not willing to participate.
• Patient with any medications that can affect their ability to engage in physical training program like Antidepressants, Beta-Blockers, corticosteroids etc.
• Pregnant women.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Пакистан · 1 центр

• Helping Hand Institute of Rehabilitation Sciences — Mansehra

Идентификаторы

NCT: NCT06846177 · Sahar Khalid

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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