Identifying Changes in Food Behaviors Associated With Beginning GLP-1 Medication

Официальное название

Exploring the Influence of GLP-1 Medication on Food Attitudes and Selection in a Virtual Reality Buffet

Обзор

In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss. Little is known, however, about how these medications may alter an individual's attitude towards food, food reactivity, or the specific types and amounts of foods an individual will choose. The purpose of this study is to observe the changes an individual experiences in their relationship and reaction to food and in their food selection prior to or within the first two weeks of taking GLP-1 medication to after three months on the medication. The researchers of this study believe that an understanding of such changes can inform questions seeking to ensure maintenance of appropriate nutrient balance within individuals on weight loss medications.

Вмешательства

• Другое GLP-1 Medication Initiation
  One visit before starting GLP-1 medication and one visit 3 months after. No other changes administered between visits.

Первичные конечные точки

• Change from Baseline in Total Weight of Food Selected in the VR Buffet at 3 Months [Срок оценки: Baseline and 3 months]
• Change from Baseline in Total Calories of Food Selected in the VR Buffet at 3 Months [Срок оценки: Baseline and 3 months]
• Change from Baseline in Energy Density of Food Selected in the VR Buffet at 3 Months [Срок оценки: Baseline and 3 months]
• Change from Baseline in Variety of Food Selected in the VR Buffet at 3 Months [Срок оценки: Baseline and 3 months]

Вторичные конечные точки (6)

• Change in Baseline Weight Watchers Food Noise Score at 3 Months [Срок оценки: Baseline and 3 months]
• Change in Baseline 9-question External Food Cue Responsiveness Questionnaire Score at 3 Months [Срок оценки: Baseline and 3 months]
• Change in Baseline Adult Eating Behavior Score at 3 Months [Срок оценки: Baseline and 3 months]
• Change in Baseline Three-Factor Eating Questionnaire Score at 3 Months [Срок оценки: Baseline and 3 months]
• Change in Baseline General Food Craving-Trait Scale Score at 3 Months [Срок оценки: Baseline and 3 months]
• Change in Baseline Buffet Food Liking Scores at 3 Months [Срок оценки: Baseline and 3 months]

Критерии участия

Критерии включения

• Adults (18+) with overweight or obesity (BMI >25 kg/m2)
• Not currently taking an incretin-based medication at baseline
• Recently (within two weeks) prescribed a GLP-1, can be included if they have a obesity-related co-occurring condition (diabetes, hypertension, cardiovascular disease, dyslipidemia)
• Have had no prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
• Fluent in English

Критерии исключения

• Adults (18+) without overweight or obesity
• <18 years of age at time of testing
• Adults not taking a GLP-1 Medication
• Adults taking a compound GLP-1
• Adults on GLP-1 medication for longer than 2 weeks at baseline
• Have had a prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
• Not fluent in English

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

США · 1 центр

• Health, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University — State College

Идентификаторы

NCT: NCT06843512 · STUDY00026642

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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