The Effect of Coconut Oil on Alopecia

Официальное название

The Effect of Coconut Oil on Alopecia in Women Receiving Doxorubucin-Cycylophosphamide Treatment for Breast Cancer

Обзор

İn this study will be conducted to evaluate the effect of coconut oil on alopecia in 86 female breast cancer patients treated at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between 01.02.2025-31.12.2025.

Подробное описание

Cancer is a disease in which the cells in our body multiply uncontrollably and develop by metastasizing, and the symptoms, course and consequences of the disease can show complex qualities in each patient. Cancer treatments have benefits and harms. One of these side effects is alopecia.

Alopecia due to cancer treatments is a condition of hair loss, partial or complete, usually temporary but rarely permanent.

In chemotherapy-induced alopecia, the hair follicle is damaged due to the pause in the anagen phase and causes the hair to break off spontaneously during activities such as washing and brushing the hair.

Various scales are used in the evaluation of alopecia due to cancer treatments, such as the National Cancer Institute Common Terminology Criteria for Side Effects and the Dean Alopecia Scale.

Some applications are made to prevent and treat alopecia. These include strategies and pharmacological applications to physically reduce the amount of medication given to the hair follicle.

Coconut oil helps regrow damaged hair. It provides essential proteins necessary for hair and softens the scalp and hair.

In the literature, it has been observed that studies showing the effects of coconut oil for the prevention and treatment of alopecia are insufficient. This study will be conducted on 86 breast cancer patients to determine the effect of coconut oil on the development of alopecia.

Вмешательства

• Другое Coconut Oil
  The coconut oil application protocol will be explained to the patients in the experimental group and 10 milliliters of coconut oil will be applied to the hair follicles once a week. Alopecia assessment will be done every week.

Первичные конечные точки

• National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia [Срок оценки: 1-12 WEEK]

Критерии участия

Критерии включения

• • To have been diagnosed with breast cancer.

• The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol.
• Volunteer to participate in the study.
• Be 18 years of age or older.
• Being a woman.

Критерии исключения

• • Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases).

• Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer.
• Not volunteering to participate in the study.
• Having previously experienced any disease/skin problem that causes hair loss.
• Having received chemotherapy before.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Поддерживающая терапия

Центры проведения

Turkey (Türkiye) · 1 центр

• Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma Hastanesi — Ankara

Идентификаторы

NCT: NCT06818370 · Ankara Onkoloji EAH

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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