Suicide Ideation in Hereditary Angioedema

This observational study focuses on patients with Hereditary Angioedema (HAE) to explore the impact of mental health on overall well-being. Through a questionnaire, the investigators aim to assess not only the presence but also the severity of suicidal thoughts, as well as symptoms of anxiety and depression. Additionally, the investigators will evaluate how these mental health factors relate to disease variables such as HAE control, disease activity, and quality of life.

Beyond mental health, the investigators also seek to understand its connection to cardiovascular risk factors. By measuring triglycerides, glucose levels, and body mass index (BMI), the investigators aim to explore whether patients with higher suicide risk also face increased heart health risks. This research will help improve patient care by emphasizing the importance of both mental and physical health in managing HAE. After identifying patients with high risk of suicide ideation the investigators will conduct a folow-up study after patients have received mental health interventions and how evaluate how treatment can determine better HAE outcomes. With these resuts the investigators expect to attract the attention of the international scientific community to increase early detection and effective solutions to prevent suicide.

• Number of participant with an increased triglyceride glucose-body mass (TyG-BMI) index [Срок оценки: In the previous 12 weeks or up to 12 weeks after enrollment]
• Number of patients with uncontrolled disease as assessed by the Angioedema Control Test (AECT) [Срок оценки: Day 1]
• Number of patients with severe disease as assessed by the Hereditary Angioedema Activity Score: HAE-AS [Срок оценки: Day 1]
• Number of patients with anxiety or depression as assessed by the Hospital Anxiety and Depression Scale (HADS) [Срок оценки: Day 1]