Milk Vs Wheat Protein Intake to Maximize Whole-body Protein Synthesis Rates in Healthy Older Adults
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: MILK, WHEAT.
- Кому может быть актуально
- Состояния в реестре: Protein Metabolism. Базовые параметры: 65 лет — 85 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Нидерланды
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
Dietary protein intake is essential for tissue renewal and growth. Current recommendations for protein intake are based on studies using egg protein as reference protein. Egg protein is an animal-based protein with a high quality. Protein quality is determined by the composition of (essential) amino acids and digestibility. Therefore, different proteins have a different quality. Due to the environmental crisis, an increasing number of people consumes more plant-based proteins. These plant-based proteins often have a lower protein quality compared to animal-based proteins. Therefore, the aim of this study is to investigate whether optimal protein intake depend on protein quality. The optimal protein intake of an animal-based protein with a high quality (milk) will be compared to the optimal protein intake of a plant-based protein with a low quality (wheat).
Вмешательства
- Другое MILK
Drink containing amino acids in the composition of milk protein - Другое WHEAT
Drink containing amino acids in the composition of wheat protein
Первичные конечные точки
- Differences in protein intake to maximize whole-body protein synthesis rates in older adults based on consumption of milk protein or wheat protein [Срок оценки: From enrollment to the end of the study at 7 weeks]
Вторичные конечные точки (4)
- Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in healthy older adults based on milk protein [Срок оценки: From enrollment to the end of the study at 7 weeks]
- The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on milk protein [Срок оценки: From enrollment to the end of the study at 7 weeks]
- The Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in older adults based on wheat protein [Срок оценки: From enrollment to the end of the study at 7 weeks]
- The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on wheat protein [Срок оценки: From enrollment to the end of the study at 7 weeks]
Критерии участия
Критерии включения
- Aged between 65-85 years
- BMI between 18.5-30 kg\*m\^-2
- Healthy, recreationally active (maximal one intensive exercise training per week)
- No physical limitations (i.e., able to perform all activities associated with daily living independently)
Критерии исключения
- Smoking
- Diagnosed musculoskeletal disorders
- Use of any medications known to affect protein metabolism (i.e., corticosteriods, non-steroidal anti-inflammatories)
- Chronic use of gastic acid-suppressing medication or anti-coagulants
- Unstable weight over the last 3 months
- Diagnosed GI tract disorders or diseases
- Blood donation in the past 2 months
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Тройное слепое
- Основная цель
- Фундаментальное исследование
Центры проведения
Нидерланды · 1 центр
- Maastricht University Medical Center+ — Maastricht
Идентификаторы
NCT: NCT06783075 · METC 24-051