Online Meditation for Mild Cognitive Impairment and Mild Dementia

Официальное название

Online Mindfulness Meditation for Mild Cognitive Impairment and Mild Dementia: a Feasibility Study

Обзор

The study will look at whether online mindfulness meditation (OMM) is easy for older adults with mild cognitive impairment (MCI) and mild dementia to use. It will also see how OMM affects their mood, sleep, and quality of life. The investigators will recruit 32 participants, divided into 4 groups of 8 people each. Participants will: * Attend an online mindfulness meditation class once a week for 8 weeks * Practice at home for 20 minutes each day * Keep a simple record of their practice and feelings

Подробное описание

This research aims to investigate the feasibility and acceptability of online meditation for older adults with mild cognitive impairment (MCI) and mild dementia in the UK and to explore its impact on cognitive function, mood, mindfulness, and quality of life. This study will recruit 32 participants with MCI and mild dementia. Participants will receive mindfulness meditation training in an online group-based format, with 8 participants per group in 4 waves. A qualified meditation teacher will lead the sessions via Microsoft Teams once a week for 8 weeks (lasting 2 to 2.5 hours per session).

The study outcomes will include feasibility of the intervention, acceptability to participants, cognitive function, mindfulness, and quality of life. Data will be collected at baseline and after the intervention. A paired t-test will compare pre- and post-intervention changes if the data meet assumptions of normal distribution and homogeneity of variance. Otherwise, non-parametric statistical analyses will be applied.

Вмешательства

• Поведенческое Online mindfulness meditation
  The mindfulness meditation program is adapted from the Breathwork Mindfulness for Stress program. However, it uses shorter meditations designed for individuals who cannot sit for 40 minutes. The mindfulness meditation program encourages greater self-acceptance, kindness, and compassion toward oneself. It builds on this concept by helping participants find pleasure in life despite suffering, fostering kindness and compassion toward others, and increasing social connections to counteract the socia

Первичные конечные точки

• Conversion rate [Срок оценки: through study completion, an average of 1 year]
• Retention rate [Срок оценки: through study completion, an average of 1 year]
• Attrition rate [Срок оценки: through study completion, an average of 1 year]
• Client Satisfaction Questionnaire [Срок оценки: immediately after the intervention]

Вторичные конечные точки (3)

• Modified Telephone Interview for Cognitive Status [Срок оценки: baseline and immediately after the intervention]
• Pittsburgh sleep quality index [Срок оценки: baseline and immediately after the intervention]
• Hospital anxiety and depression scale [Срок оценки: baseline and immediately after the intervention]

Критерии участия

Критерии включения

• Age 60 years or older.
• MCI: Concern regarding a change in cognition, with impairment in one or more cognitive domains, including memory, executive function, attention, language, and visuospatial skills. Preservation of independence in functional abilities and does not meet the criteria for dementia, as described in the National Institute on Aging and Alzheimer's Association (NIA-AA) diagnostic guidelines.
• Mild dementia: As described in the NIA-AA research framework, mild dementia is defined as substantial progressive cognitive impairment affecting several domains and/or neurobehavioral disturbances. Documented by the individual's report, an observer (e.g., a study partner) report, or by changes observed on longitudinal cognitive testing. Clearly evident functional impact on daily life, mainly affecting instrumental activities. No longer fully independent and requires occasional assistance with daily activities.
• Access to an electronic device (e.g., smartphone, computer, or tablet) and the internet.
• Ability and willingness to provide informed consent by signing the Consent Form.

Критерии исключения

• Current active or past significant experience with meditation.
• Clinically significant mental or physical health disorder beyond MCI or dementia that may affect cognition and/or the ability to complete the study (e.g., severe depression, suicidality, psychosis, post-traumatic stress disorder (PTSD), major psychiatric diagnoses, social anxiety (e.g., difficulty participating in a group setting), or severe impairments in eyesight, hearing, or upper limb motor movements).
• Inability to commit to attending classes (e.g., planning to miss three or more classes).
• Lack of proficiency in English.
• Diagnosed with moderate or severe dementia.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Не применимо

Модель

Одна группа

Маскирование

Открытое

Основная цель

Поддерживающая терапия

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

• You J, Khan Z, Swaroop R, Sun Y, Velayudhan L, Aarsland D. Online mindfulness meditation for mild cognitive impairment and mild dementia: A feasibility study protocol. PLoS One. 2025 Nov 25;20(11):e0336583. doi: 10.1371/journal.pone.0336583. eCollection 2025. PMID 41289241

Идентификаторы

NCT: NCT06768450 · 341708 · 341708

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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