Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Face mask containing Centella sinensis.
- Кому может быть актуально
- Состояния в реестре: Rosacea, Acne, Centella, Melasma. Базовые параметры: 18 лет — 60 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases. A multi-center randomized double-blind self-half face control method was used. A computer-generated randomization method was used. Each cheek was randomly assigned to receive the snow glycoside mask and the control group.
Вмешательства
- Другое Face mask containing Centella sinensis
A half-face control test was used in this study. One side of the face was treated with a mask containing Asiaticum asiatica and the other side was treated with a mask without Asiaticum asiatica
Первичные конечные точки
- Clinical erythema Score (CEA) [Срок оценки: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.]
- Global Aesthetic Improvement Scale Score (GAIS) [Срок оценки: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.]
- Melasma Area and Severity Rating (MASI) [Срок оценки: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.]
Вторичные конечные точки (1)
- Dermatology Quality of Life Score (DLQI) [Срок оценки: Patients were followed up on the day of treatment and at 1, 2, 3, 4, 6, and 8 weeks after treatment.]
Критерии участия
Критерии включения
- Meet mild to moderate rosacea, acne diagnostic criteria; Meet the diagnostic criteria for melasma;
- Over 18 years of age;
- Be able to follow the treatment rules of the study and be followed for 8 weeks;
- Informed consent; 5There were no significant cardiac, liver, kidney, gastrointestinal, neurological, psychiatric, or metabolic disorders
6.No medication was used within 1 month
Критерии исключения
- Currently pregnant, planning to become pregnant or breastfeeding;
- Documented hypersensitivity to any active ingredient or excipient included in the study drug, or a history of adverse reactions to cosmetic products;
- Participate in other clinical studies within 3 months before the start of the study;
- Frequent use of Chinese medicine, sleeping pills, sedatives, anti-anxiety drugs or potentially addictive substances;
- Present with concomitant skin conditions that may confuse the clinical assessment of rosacea, melasma, seborrheic dermatitis or pose a risk to participants, or have a history of severe skin conditions;
- Normal use of relevant treatment (including intense pulsed light, pulsed fuel laser, oral and topical tranexamic acid, oral tetracycline antibiotics, oral compound glycyrrhizin and other anti-inflammatory drugs)
- Patients with incomplete observation data, incomplete course of treatment and inability to take drugs as prescribed by doctors were removed
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Одна группа
- Маскирование
- Открытое
- Основная цель
- Лечение
Центры проведения
Китай · 1 центр
- Nanjing First Hospital — Нанкин
Идентификаторы
NCT: NCT06763367 · KY20241217-04