Exploring the Effects of Aerobic Exercise Combined with BFRT on Patients with COPD
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Aerobic exercise intervention, Disease and exercise suggestion, Blood flow restriction (BFR) intervention.
- Кому может быть актуально
- Состояния в реестре: Chronic Obstructive Pulmonary Disease. Базовые параметры: 30 лет — 85 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Тайвань
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Exploring the Effects of Aerobic Exercise Combined with Blood Flow Restriction Training on Exercise Capacity, Cardiopulmonary Functions, and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease
Обзор
Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in COPD patients.
Подробное описание
The systemic effects of Chronic Obstructive Pulmonary Disease (COPD) can precipitate a series of complications, including cardiovascular disorders, muscle atrophy, and osteoporosis. These comorbid conditions often result in decreased physical activity and suboptimal physical fitness, compelling patients to lead a sedentary lifestyle to mitigate exercise-induced dyspnea. Addressing the limitations in exercise tolerance remains a critical therapeutic goal in the treatment of COPD. According to research, exercise intolerance is caused by both poor pulmonary function and associated skeletal muscle dysfunction. Blood flow restriction training, a new rehabilitation technique, has shown promise in improving muscular strength at lower exercise intensities and in shorter timeframes, presenting a fresh approach to COPD rehabilitation.
The research aims to investigate the impact of incorporating blood flow restriction training into a holistic aerobic exercise program on exercise capacity and quality of life among patients with COPD. The findings are intended to clarify the potential of this innovative training technique as a supplementary therapeutic strategy in the management of COPD.
Вмешательства
- Поведенческое Aerobic exercise intervention
The aerobic exercise intervention will utilize an ergometer. The program will be conducted 2-3 times per week over a 3-month period. - Поведенческое Disease and exercise suggestion
The participants will be provided by educational program about COPD self-care and home-based exercise approach. - Поведенческое Blood flow restriction (BFR) intervention
Blood flow restriction (BFR) intervention will combine aerobic exercise on the ergometer with BFR training. The program will be conducted 2-3 times per week over a 3-month period.
Первичные конечные точки
- Oxygen consumption (VO2) [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Diaphragm capacity [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
Вторичные конечные точки (7)
- Functional capacity [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Heart Rate Variability [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Pulmonary function test [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Maximum respiratory pressure [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Quality of life score (COPD-related questionnaire-I) [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Quality of life score (COPD-related questionnaire-II) [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
- Quality of life score (COPD-related questionnaire-III) [Срок оценки: Change from baseline (0 week) to follow up (20 weeks)]
Критерии участия
Критерии включения
- COPD classified as levels 2-4.
- Stable condition without worsening in the past three months.
- No participation in any rehabilitation program within the past six months.
- Ability to understand and follow verbal commands and cooperate with an exercise training program.
Критерии исключения
- Unconscious or unable to cooperate with the evaluator.
- Hospitalization due to acute illness within the past three months.
- Severe joint diseases or history of lower limb surgery.
- Severe cardiovascular disease (e.g., presence of a cardiac pacemaker or acute myocardial infarction within the past six months).
- Dependence on oxygen supply.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Открытое
- Основная цель
- Профилактика
Центры проведения
Тайвань · 1 центр
- National Cheng Kung University Hostipal — Tainan
Идентификаторы
NCT: NCT06756646 · B-ER-113-298