Набор скоро начнётся NCT06752655

Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer

Без фазы С лечением Periapical Diseases Postoperative Dental Pain Irrigation Solution Photodynamic Therapy (PDT)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Curcumin with photodynamic thearpy, Control group.
Кому может быть актуально: Состояния в реестре: Periapical Diseases, Postoperative Dental Pain, Irrigation Solution, Photodynamic Therapy (PDT). Базовые параметры: 18 лет — 60 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Turkey (Türkiye)
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

The Effect of Photodynamic Therapy Using Curcumin As a Photosensitizer on Postoperative Pain After Non-Surgical Root Canal Retreatment: a Randomized Controlled Clinical Trial

Обзор

In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has been demonstrated in several studies. However, no research has specifically examined their effect on postoperative pain. The aim of this study is to investigate the impact of using a curcumin solution in combination with photodynamic therapy as the final irrigation solution on postoperative pain.

Подробное описание

Fifty patients were randomly assigned to two groups using a web-based program, according to the selected final irrigation procedure: curcumin-photodynamic therapy or a control group (routine root canal final irrigation with NaOCl and EDTA). The teeth will be isolated with a rubber dam, and access cavities will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will then be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.

Вмешательства

Другое Curcumin with photodynamic thearpy
root canals will irrigated with final irrigation procedure: curcumin+photodynamic therapy. The teeth will be isolated with a rubber dam, and an access cavity will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.
Другое Control group
root canals will irrigated with routine root canal final irrigation with NaOCl and EDTA. The teeth will be isolated with a rubber dam, and an access cavity will be created. After root canal preparation, the final irrigation procedure will be performed. Root canal treatments will be completed, and the patients' postoperative pain levels will be recorded using follow-up forms.

Первичные конечные точки

postoperative pain levels [Срок оценки: one week]

Вторичные конечные точки (4)

dependent variables-sex [Срок оценки: one week]
dependent variable-age [Срок оценки: one week]
dependent variables-teeth number [Срок оценки: one week]
dependent variables-smoking habit [Срок оценки: one week]

Критерии участия

Критерии включения

healthy patients with aged between 18-60.
Incisor, canine, and premolar teeth that had previously undergone root canal treatment
Incisor, canine, and premolar teeth with a diagnosis of chronic apical abscess or asymptomatic apical periodontitis
teeth with only 1 root canal
the patients had not used any antibiotics for 3 months before treatment