Идёт набор NCT06727500

Effects of HIIT and Concurrent HITT/Plyometric Training on Muscle-tendon Structure, Function and Metabolism in Pediatric Population With Obesity at Different Biological Maturation States (HIIT-PRO Kids).

Без фазы С лечением Pediatric Obesity Training Effectiveness

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: HIIT plus plyometric training, HIIT.
Кому может быть актуально: Состояния в реестре: Pediatric Obesity, Training Effectiveness. Базовые параметры: 7 лет — 17 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Чили
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Effects of HIIT and Concurrent HITT/Plyometric Training on Muscle-tendon Structure, Function and Metabolism in Pediatric Population With Obesity at Different Biological Maturation States (HIIT-PRO Kids): A Study Protocol of Randomized Controlled Trial

Обзор

The randomized controlled trial will compare the effects of a High-intensity interval training (HIIT) protocol versus a HIIT plus plyometric training in the muscle-tendon structure function and metabolism of the pediatric population with obesity at different biological maturational stages (pre-to-age peak velocity \[APHV\] and post-APHV). Both groups perform baseline evaluations of the main and secondary outcomes and receive the intervention for twelve weeks, three times per week. Once the interventions are completed, the participants undergo the same evaluations they performed at baseline.

Подробное описание

The prevalence of pediatric obesity increased 4.2-fold between 1976 and 2022, and it's expected to continue increasing toward 2030. Pediatric obesity is a public health problem due to its multiple metabolic comorbidities. Moreover, body weight and fat infiltration due to pediatric obesity negatively affect muscle-tendon structure, function, and metabolism, negatively impacting physical activity levels, active play, functional performance (e.g., jumping capacity), and quality of life. As a solution, HIIT protocols could decrease body weight and fat percentage and increase muscle oxidative capacity. The addition of plyometric training to HIIT protocols could generate the same effects as the HIIT protocol alone, with an additional enhancement in functional performance. However, the influence of biological maturation stages in the adaptations to training in pediatric population with obesity has been scarcely reported. Thus, throughout different biological maturation stages, such as pre-to-age peak velocity (APHV) (early stage of biological maturation) to post-APHV (final stage of biological maturation stage), an increase in testosterone, growth factors, and glycolytic metabolism capacity occurs. Therefore, the differences in the anabolic milieu and glycolytic metabolism between the pre-APHV and post-APHV could produce a differential capacity of training stimuli to modify the muscle-tendon, structure, function, and metabolism in these pediatric population with obesity. Therefore, this study aims to determine the effects of HIIT and concurrent HIIT and plyometric training in the muscle-tendon structure, function, and metabolism of the pediatric population with obesity in different maturation stages.

The study will be a parallel-group randomized controlled trial that compares the effects of HIIT versus HIIT plus plyometric training on muscle-tendon structure, function, and metabolism in the pediatric population pre-APHV and post-APHV with obesity in a public health setting. The primary outcome will be the Achilles tendon mechanical properties. We estimate a sample size of 10 participants per group and 40 in total.

The investigators aim to demonstrate the beneficial effects of HIIT plus plyometric training on the muscle-tendon structure and metabolism of the pediatric obesity population. Moreover, the researchers expected a difference in the adaptations provided by the training protocol between the pre-APHV and post-APHV groups.

Вмешательства

Поведенческое HIIT plus plyometric training
The HIIT plus plyometric training will perform two weeks of exercise adaptation involving 25 minutes of MICT at 65% of maximal heart rate (HRmax) and 5 minutes of jumps in place at 5 - 6 of the EPinfant scale of Perceived exertion. The HIIT plus plyometric training will perform 15 minutes of HIIT and 5 minutes of jumps each session. The HIIT phase will be performed in a work recovery intensity at 85 and 50% of the HRmax. The work phase of jumps will be performed "all out," and the recovery phase
Поведенческое HIIT
The HIIT group will perform two weeks of exercise adaptation involving 30 minutes of moderate-intensity continuous training (MICT) at 65% of the maximal heart rate (HRmax) reached in the maximal oxygen consumption test. The HIIT group will perform 20 minutes of HIIT each session, with a work: recovery intensity at 85% and 50% of HRmax, respectively. The work: recovery bouts will be progressed from 1:4 (15 seconds:60 seconds) at weeks 3-6, to 1:3 (15 seconds:45 seconds) at weeks 7-9, and to 1:2 (

Первичные конечные точки

Achilles Tendon Stiffnes (N/mm) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]

Вторичные конечные точки (12)

Achilles Tendon Young Modulus [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Achilles Tendon Force (N) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Achilles Tendon Elongation (mm) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Achilles Tendon Stress (MPa) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Achilles Tendon Strain (%) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Gastrocnemius Medialis Thickness (mm) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Gastrocnemius Medialis Pennation Angle (°) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Gastrocnemius Medialis Fascicle Length (mm) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Gastrocnemius Medialis Echo-Intensity (U.A). [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Plantar Flexors Maximal Isometric Voluntary Contraction (Nm) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Plantar Flexors Rate of Force Development (Nm/s) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]
Maxymal Oxygen Consumption (ml/kg/min) [Срок оценки: Previous (T0) and posterior to twelve weeks of training (T12).]

Критерии участия

Критерии включения

Pediatric population with obesity determined by the body mass index by z-score (BMI-z) ≥ 2 standard deviations (SD) and ≤ 3.5 SD of the median for age and sex.
Pediatric population with -1 to -3 APHV (pre-APHV) and +1 to +3 APHV (post-APHV).