Меню
Набор скоро начнётся NCT06722092

VR and Scrip Training of PWA, Randomized Controlled Trial

Без фазы С лечением Aphasia, Acquired Chronic Stroke

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: VR-based script training, Conventional script training.
Кому может быть актуально
Состояния в реестре: Aphasia, Acquired, Chronic Stroke. Базовые параметры: 30 лет — 80 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

Can Immersive Virtual Reality Magnify Treatment Outcomes of Script Training on Cantonese Speakers with Chronic Aphasia: a Randomized Controlled Trial

Обзор

The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes. The main research questions are: 1. Can script training promote verbal functional communication of Cantonese-speaking PWA? 2. Can script training enhance nonverbal cognitive functions of Cantonese-speaking PWA? 3. Can VR magnify verbal and nonverbal treatment outcomes of script training of PWA?

Вмешательства

  • Поведенческое VR-based script training
    The PWA will wear a head-mounted VR device (e.g., Metaverse Oculus Quest 2 or other commercially available devices) for 30 minutes, which intends to create an immersive environment for training. Scripts trained in the computerized script training program in a particular session will be practiced. Cinematic 360˚ photo-real scenarios of daily contexts such as a restaurant or a grocery store will be displayed in the device while a communication partner, e.g., a waiter in the restaurant or a shopkee
  • Поведенческое Conventional script training
    The flow of training is identical to the VR condition, except that photos depicting the scenarios and prerecorded conversational turns will be presented to the PWA on a computer screen with the same procedures mentioned in the VR condition.

Первичные конечные точки

  • Percentage accuracy of treatment probe correctly produced [Срок оценки: From baseline up to 8-week post training]
  • Time to produce each of the scripts in the treatment probe [Срок оценки: From baseline up to 8-week post training]
  • Number of sessions to reach performance criteria in session probe [Срок оценки: From baseline up to 8-week post training]
Вторичные конечные точки (7)
  • Cantonese version of the Western Aphasia Battery (CAB) to measure aphasia severity [Срок оценки: From baseline up to 8-week post training]
  • Cantonese version of the Amsterdam-Nijmegen Everyday Language Test to measure verbal communication effectiveness in conversation via 20 culturally appropriate scenarios [Срок оценки: From baseline up to 8-week post training]
  • Cantonese version of the 20-item Communication Outcome after Stroke (Can-COAST) as a self-reported outcome on communication and quality of life [Срок оценки: From baseline up to 8-week post training]
  • Subtest 1 (map search) and 3 (elevator counting) of Test of Everyday Attention to assess attention [Срок оценки: From baseline up to 8-week post training]
  • Digit span forward and backward task to assess verbal short-term and working memory [Срок оценки: From baseline up to 8-week post training]
  • Test of Nonverbal Intelligence-third edition (TONI-3) to assess executive function [Срок оценки: From baseline up to 8-week post training]
  • Wisconsin Card Sort Test (WCST) to assess executive function [Срок оценки: From baseline up to 8-week post training]

Критерии участия

Критерии включения

  • a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
  • premorbid fluent Cantonese speakers,
  • aged between 30 and 80 years,
  • no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
  • no motor speech disorders of moderate to severe level, and
  • normal or corrected-to-normal vision and hearing functions

Критерии исключения

  • concurrent participation in other aphasia treatment trials, and
  • incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Простое слепое
Основная цель
Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

  • Wong WWS, Li DSP, Fong KNK, Ng PHF, Kwok HTK. Can immersive virtual reality magnify treatment outcomes of computerized script training on Cantonese speakers with chronic aphasia? Protocol of a randomized controlled trial. PLoS One. 2026 Jun 2;21(6):e0350390. doi: 10.1371/journal.pone.0350390. eCollection 2026. PMID 42228712

Идентификаторы

NCT: NCT06722092 · HSEARS20230228003-01

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗