Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry

Detailed Description Stroke is a leading cause of morbidity and mortality worldwide, with a significant burden in the MENA region due to limited access to advanced stroke care therapies like mechanical thrombectomy (MT). The MEMENTO Registry seeks to collect real-world data on MT practices, outcomes, and accessibility in the MENA region to inform clinical practice and policy. The study includes AIS patients who underwent MT for confirmed LVO or medium vessel occlusion (MeVO), with or without prior intravenous thrombolysis (IV tPA), regardless of age, baseline NIHSS score, or time from symptom onset.

Data collected encompass demographics, clinical characteristics, imaging findings, procedural details, outcomes at discharge and follow-up, complications, and a cost-effectiveness analysis comparing MT to standard medical care (SMC). The primary outcome is functional independence at 90 days post-procedure, defined as a modified Rankin Scale (mRS) score of 0-2.

• Proportion of Patients Achieving TICI Score ≥2b After MT [Срок оценки: Immediately post-procedure]
• Improvement in NIHSS Score from Baseline to 24 Hours and at Follow-up [Срок оценки: Baseline, 24 hours, and up to 90 days]
• Symptomatic Intracerebral Hemorrhage (sICH) Rate [Срок оценки: Within 7 days post-procedure]
• All-Cause Mortality at 90 Days [Срок оценки: 90 days post-procedure]
• Complication Rate [Срок оценки: Immediately post-procedure up to 7 days]
• Incremental Cost-Effectiveness Ratio (ICER) per Quality-Adjusted Life Year (QALY) Gained [Срок оценки: From baseline (pre-procedure) through 90 days post-procedure, with economic modeling extended to a lifetime horizon (up to 20 years)]