Идёт набор NCT06697964

High Resolution Anuscopy Study

— Наблюдательное Human Papilloma Virus Anal Squamous Cell Carcinoma

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: HRA.
Кому может быть актуально: Состояния в реестре: Human Papilloma Virus, Anal Squamous Cell Carcinoma. Базовые параметры: от 18 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Бельгия
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Обзор

The majority of anal squamous cell carcinomas (SCC) stem from infection with high-risk human papillomavirus (HPV). Anal SCC is rare among the general population but affects several populations disproportionately. High-risk groups are screened through anal swabs for anal cytology and detection of high risk human papillomavirus (HR HPV). HRA referral is recommended for individuals with abnormal cytology. HRA represents the only method to identify precancerous lesions of the anal canal, with only few specialists knowledgeable about it. At UZ Brussel, the investigators collected a wealth of data about HPV infection and its association with anal pathology. By establishing a comprehensive study, the investigators can delve into this data with specific research questions, conducting valuable research to provide answers to pressing clinical questions and contribute to advancements in medical understanding and treatment.

Вмешательства

Другое HRA
High resolution anoscopy to help evaluate anal conditions such as precancerous lesions

Первичные конечные точки

comparison of the prevalence of precancerous lesions in men who have sex with men using PrEP or are HIV positive Men [Срок оценки: Through study completion, on average 5 years]
Exploration of associations between abnormal histology and patient characteristics [Срок оценки: Through study completion, on average 5 years]
comparison of the prevalence of precancerous lesions in different groups [Срок оценки: Through study completion, on average 5 years]
to delineate unique features associated with HSIL in each risk group by linking patterns or characteristics [Срок оценки: Through study completion, on average 5 years]
Prevalence of anal cancer among the at-risk populations [Срок оценки: Through study completion, on average 5 years]
correlation between abnormal histology and abnormal cytology, as well as HPV infection in MSM using PrEP and MSM living with HIV [Срок оценки: Through study completion, on average 5 years]

Критерии участия

Критерии включения

All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel
18 years or older
Understands and able to speak and write in French, Dutch or English