Меню
Набор скоро начнётся NCT06693141

Effects of Erector Spinae Plane Block and Intrathecal Morphine Administration on Intraoperative Sevoflurane Consumption

— Наблюдательное Postoperative Pain Anesthesia

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: ESP block, ITM.
Кому может быть актуально
Состояния в реестре: Postoperative Pain, Anesthesia. Базовые параметры: 18 лет — 65 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Turkey (Türkiye)
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

Comparison of the Effects of Erector Spinae Plane Block and Intrathecal Morphine Administration on Intraoperative Sevoflurane Consumption in Disc Surgeries

Обзор

In our study, the investigators aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.

Подробное описание

The amount of volatile anesthetic agents used for anesthesia maintenance can be significantly reduced with potent and long-acting analgesic interventions administered during the preoperative period. Such interventions enable the maintenance of anesthesia with more optimal levels of agents during surgery, providing significant advantages in terms of both patient safety and cost.

Studies have recommended multimodal analgesia approaches involving the Erector Spinae Plane (ESP) block and intrathecal morphine (ITM) injection for various surgical procedures. These two methods, through different mechanisms of action, not only reduce intraoperative anesthetic agent consumption but also play a critical role in postoperative pain management. Although studies have investigated the effects of ESP block and ITM injection on intraoperative volatile anesthetic consumption, there is limited research directly comparing their impacts on volatile anesthetic consumption and postoperative analgesic requirements.

In our study, we aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.

Вмешательства

  • Другое ESP block
    ESP block was applied to the patients.
  • Другое ITM
    ITM was applied to the patients.

Первичные конечные точки

  • Intraoperative Sevoflurane consumption [Срок оценки: 60 minutes after anesthesia induction]
Вторичные конечные точки (5)
  • Rescue analgesic consumption [Срок оценки: 2 hours postoperatively]
  • Rescue analgesic consumption [Срок оценки: 4 hours postoperatively]
  • Rescue analgesic consumption [Срок оценки: 8 hours postoperatively]
  • Rescue analgesic consumption [Срок оценки: 12 hours postoperatively]
  • Rescue analgesic consumption [Срок оценки: 24 hours postoperatively]

Критерии участия

Критерии включения

  • Patients aged over 18 years
  • Patients receiving general anesthesia
  • Patients with an ASA score of I-II
  • Patients undergoing elective surgery for single-level lumbar disc herniation
  • Patients who provided informed consent after being informed

Критерии исключения

Patients who did not provide informed consent after being informed

  • Patients over 65 years of age
  • Patients with an ASA score of III or higher
  • Patients with recurrent lumbar disc herniation (LDH)
  • Patients undergoing surgery for multi-level LDH
  • Patients with a body mass index (BMI) of 30 or higher
  • Patients with allergies to morphine or bupivacaine
  • Patients with major cardiac, respiratory, hepatic, renal, neurological, or psychiatric diseases
  • Patients with a history of alcohol or substance abuse
  • Patients with a local infection at the injection site
  • Patients with bleeding diathesis
  • Patients with a history of anticoagulant medication use
  • Patients with contraindications to spinal or regional anesthesia

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Дизайн исследования

Модель наблюдения
Случай-контроль

Центры проведения

Turkey (Türkiye) · 1 центр
  • Ankara Etlik City Hospital — Ankara

Публикации

  • Yorukoglu HU, Icli D, Aksu C, Cesur S, Kus A, Gurkan Y. Erector spinae block for postoperative pain management in lumbar disc hernia repair. J Anesth. 2021 Jun;35(3):420-425. doi: 10.1007/s00540-021-02920-0. Epub 2021 Mar 22. PMID 33751203
  • Lal A, Singh MK, Kanaujia SK, Mishra NK, Singh BP, Singh GP. Comparison of Intrathecal Morphine Versus Erector Spinae Plane Block for Perioperative Analgesia in Patients Undergoing Lumbar Spine Surgery: A Randomized Control Trial. Cureus. 2024 Jul 17;16(7):e64775. doi: 10.7759/cureus.64775. eCollection 2024 Jul. PMID 39156461
  • Nashibi M, Sezari P, Safari F, Teymourian H, Asgari S, Mottaghi K. The effect of erector spinae plane block on the use of anesthetic medications in lumbar spine surgery. Agri. 2023 Oct;35(4):228-235. doi: 10.14744/agri.2022.48992. PMID 37886866

Идентификаторы

NCT: NCT06693141 · Bengü Tez

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗