Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department

Официальное название

Randomized Controlled Trial of a Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department

Обзор

When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour. There is no established evidence-based brief treatment for patients with BPD in ED settings, however a 4-session treatment for people with personality disorders in ED settings was tested in Australia and showed promising results in reducing health care use and improving symptoms. A recent pilot feasibility randomized controlled trial (RCT) comparing this 4-session treatment to treatment as usual was conducted at the Centre for Addiction and Mental Health and preliminary findings have shown that the treatment is feasible to deliver and acceptable to both patients and clinicians. The proposed fully powered RCT will build on this pilot data to assess the efficacy of delivering this 4-session intervention in the ED for people with BPD who present with suicidal ideation or self-harm with the aim of reducing emergency health care use and improving BPD symptoms, functioning and quality of life.

Вмешательства

• Поведенческое Gold Card Intervention
  A 4-session manualized intervention consisting of weekly scheduled 50-minute 1:1 sessions focused on psycho-education, here-and-now problem solving and safety planning. One of the sessions can involve a significant other to provide psychoeducation about the disorder and to facilitate support.
• Поведенческое Treatment as usual
  Access to psychiatric assessment, medication review, and unscheduled sessions with allied health professionals using a drop-in model of care.

Первичные конечные точки

• Suicidal Ideation [Срок оценки: 6 Month Follow Up]

Вторичные конечные точки (8)

• Suicidal Ideation [Срок оценки: 3 Month Follow Up]
• Health Care Use [Срок оценки: 3 and 6 Month Follow Up]
• Borderline Personality Disorder Symptoms [Срок оценки: 3 and 6 Month Follow Up]
• Self-Harm Behavior [Срок оценки: 3 and 6 Month Follow Up]
• Emotion Regulation [Срок оценки: 3 and 6 Month Follow Up]
• Depressive Symptoms [Срок оценки: 3 and 6 Month Follow Up]
• Functioning [Срок оценки: 3 and 6 Month Follow Up]
• Quality of Life [Срок оценки: 3 and 6 Month Follow Up]

Критерии участия

Критерии включения

• Must be deemed to have capacity to provide informed consent;
• Must sign and date the informed consent form;
• Stated willingness to comply with all study procedures;
• Aged 16 or older;
• Presenting to ED with self-harm and/or suicidal ideation;
• Meeting criteria for BPD on the International Personality Disorders Examination (IPDE).
• Endorsing a score of 1 or greater on the Suicide Ideation Attributes Scale (SIDAS).

Критерии исключения

• Meeting DSM-5 criteria for schizophrenia spectrum disorder or bipolar disorder I mania based on the Structured Clinical Interview for DSM-5 (SCID-5);
• Severe alcohol or substance use disorder based on the Structured Clinical Interview for DSM-5 (SCID-5) requiring medical detoxification or residential treatment.
• IQ < 70 based on the Test of Premorbid Functioning (TOPF).

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Канада · 1 центр

• Centre for Addiction and Mental Health — Toronto

Идентификаторы

NCT: NCT06675461 · 2022-081

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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