Erythropoietin Gel Effect on Dental Implant Stability

Официальное название

Evaluation of Erythropoietin Gel Effect on Stability of Immediate Implant ( Clinical and Radiographical Study )

Обзор

* Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants. Numerous coating techniques have been developed to improve and speed up osseointegration. * The aim of the current study is to assess immediate dental implant stability coated with erythropoietin gel, both clinically and radiographically. * Materials and Methods: We conducted a randomized controlled clinical trial.The sample will include patients demanding immediate implant treatment in the anterior maxilla . Patients will be randomly allocated into the two groups of the study. The group A will be treated with erythropoietin gel coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . Group B will be treated with non coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . * The primary outcome variable will be implant stability and the secondary outcome will be crestal marginal bone level and bone density around implants. It will be measured at time of implant placement and reevaluated after 6-months .

Вмешательства

• Другое Non coated dental implants
  Patients with fresh extraction sockets in the anterior maxilla will be treated by non coated immediate implant .
• Другое Erythropoietin gel coated implants
  Patients with fresh extraction sockets in the anterior maxilla will be treated by immediate implant coated by erythropoietin gel.

Первичные конечные точки

• Change in implant stability [Срок оценки: Baseline and after 6 month]

Вторичные конечные точки (1)

• Change in marginal bone level and bone density around implants [Срок оценки: Baseline and after 6 month]

Критерии участия

Критерии включения

• All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement.
• Good general periodontal health and maintenance.

Критерии исключения

• Heavy smokers who smoke more than ten cigarettes per day
• Acute infected socket
• Ant socket with wall defect.
• Pregnency
• Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease.
• Patients who had subjected to intravenous and/or oral bisphosphonate therapy.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Египет · 1 центр

• Faculty of dental medicine Al-Azhar university — Asyut

Идентификаторы

NCT: NCT06665451 · Implant surface modification

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗