Effect of Pelvic Floor Down-training on Women With Idiopathic Overactive Bladder

Обзор

This study will be conducted to investigate the effect of pelvic floor down-training on women with idiopathic overactive bladder

Подробное описание

The relationship between overactive bladder (OAB), constipation, and overactive pelvic floor muscles is complex and interrelated. OAB increases the likelihood of overactive pelvic floor muscles, and conversely, hyperactive pelvic floor muscles can exacerbate OAB symptoms. Non-relaxing pelvic floor dysfunction often presents with urinary symptoms, including increased frequency, hesitancy, urgency, dysuria, bladder pain, and occasionally urge incontinence Pelvic floor down-training exercises targeting the rectum provide a safe, conservative way to manage constipation, which may in turn help relieve OAB. Unlike medications or surgery; these exercises are generally safe and easy to incorporate into daily life. However, more studies are needed to evaluate their effectiveness, especially for treating idiopathic OAB in women. Filling this research gap will provide clearer clinical guidance on managing the interplay between OAB, constipation, and pelvic floor hyperactivity. So this study will be the first to investigate the effect of pelvic floor down-training on symptoms of idiopathic OAB in women.

Вмешательства

• Поведенческое Behavioral modification
  It includes: .- Reducing or eliminating smoking and carbonated drinks. * Weight loss in overweight or obese individuals. * Caffeine Reduction: Limiting caffeine intake, especially for those consuming at least 400 mg per day. * Consume Adequate Water: 6 to 8 glasses of water per day. * Refrain from consuming fluids 2 to 3 hours before bedtime. * Identify Bladder Irritants: such as sugar substitutes, citrus fruits, and tomato. * Increasing fiber intake like fruits, and vegetables to reduce const
• Другое Pelvic floor down-training
  Pelvic floor down training exercises aimed at promoting relaxation and deconditioning of the pelvic floor muscles (PFM). It will be practiced three sessions per week for 8 weeks. Biofeedback-Assisted pelvic floor down-training: Procedure: * Rectal biofeedback will be inserted. * The therapist asks the woman to focus on consciously relaxing and releasing the PFM after each contraction or exercise while watching biofeedback screen. * Then, breathe deeply and fully into her abdomen, allowing her

Первичные конечные точки

• Rectal resting pressure [Срок оценки: 8 weeks]
• Rectal bearing pressure [Срок оценки: 8 weeks]
• Overactive Bladder Symptom Score (OABSS): [Срок оценки: 8 weeks]
• Assessment of overactive bladder symptoms [Срок оценки: 8 weeks]
• Assessment of quality of life [Срок оценки: 8 weeks]
• Constipation scoring system [Срок оценки: 8 weeks]
• Five-item score for obstructed defecation syndrome (ODS-S) [Срок оценки: 8 weeks]

Критерии участия

Критерии включения

• Multiparous woman with idiopathic OAB (2-3 times) who diagnosed by physician and confirmed by the urodynamic study.
• Woman with high rectal resting tone measured by pressure biofeedback.
• Woman diagnosed with constipation according to the Rome IV criteria and Bristol score.
• Ages ranging from 30 to 45 years.
• BMI from 25-29.9 Kg/m2

Критерии исключения

Women will be excluded from the study if they have:

• Severe OAB as measured by the overactive bladder symptom score for severity
• Postmenopausal women (a point in time 12 months after a woman's last period.)
• Any abnormalities around the bladder, such as bladder cancer, bladder calculus, interstitial cystitis, or endometriosis.
• Untreated urinary tract infections.
• Psychological or mental health problems.
• Pregnancy and lactation
• A history of previous pelvic surgery.
• Are receiving any pharmacological treatment at the time of the study.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Египет · 1 центр

• Ayatullah Farouk Abdel Fattah — Cairo

Идентификаторы

NCT: NCT06662565 · P.T.REC/012/005319

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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