Набор скоро начнётся NCT06631885

Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth

Без фазы С лечением Immature Teeth Necrotic Pulp

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: regenerative endodontic procedure using blood clot according to AAE, regenerative endodontic procedure using photo activated nanochitosan 2%.
Кому может быть актуально: Состояния в реестре: Immature Teeth, Necrotic Pulp. Базовые параметры: Без ограничений · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Список центров уточняется — проверьте первичный протокол.
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Efficacy of Integrated Nano-technology in the Irrigation Protocol of Revascularization Technique In Immature Necrotic Teeth (Randomized Clinical Trial)

Обзор

This trial aims to study the effect of photoactivated disinfection using Diod laser (810 nm) to activate photosensitive nanoparticle chitosan as an endodontic irrigant versus sodium hypochlorite followed by saline and then EDTA 17% on 1) postoperative pain and 2) the success of revascularization in patients with necrotic immature maxillary anterior teeth using a randomized clinical trial design.

Подробное описание

randomized clinical trial will be conducted to investigate and compare the efficacy of photosensitized nano-chitosan 2% as an endodontic disinfectant during revascularization versus sodium hypochlorite, followed by EDTA 17% according to the standardized protocol of the American Association of endodontics.

Twenty individuals with necrotic, immature permanent anterior teeth will be recruited. They will be randomly assigned into two groups according to the received intervention: control group and test group.

pain will be evaluated as a primary outcome at 24 hours and one week post-intervention using numerical rating scale (NRS). In addition, the root development in terms of change in root length and apical foramen diameter and periapical bone healing will be evaluated as secondary outcomes using cone beam tomography.

Вмешательства

Процедура regenerative endodontic procedure using blood clot according to AAE
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using AAE protocol
Процедура regenerative endodontic procedure using photo activated nanochitosan 2%
regenerative endodontic procedure using blood clot to replace the necrotic pulp tissues in immature teeth with a pulp like to tissue to complete root development. using photosensitized nanochitosan for root canal disinfection

Первичные конечные точки

pain intensity assessed by numerical rating scale [Срок оценки: 24 hours and 1 week after completion of the procedure]

Вторичные конечные точки (3)

root development [Срок оценки: 6 months, 1 year postoperative]
Apical foramen closure [Срок оценки: 6 months, 1 year postoperative]
periapical bone healing [Срок оценки: 6 months, 1 year postoperative]

Критерии участия

Критерии включения

o Immature necrotic maxillary incisor with open apex greater than 1 mm.

Teeth where pulp space are not needed for post and core.
A restorable tooth.
Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
Patients who will agree to the consent and will commit to follow-up period.