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Идёт набор NCT06606704

Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults

Без фазы С лечением Aging

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Creatine Bolus 5, Creatine Bolus 3, Creatine Intermittent 5, Placebo.
Кому может быть актуально
Состояния в реестре: Aging. Базовые параметры: от 50 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Канада
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults

Обзор

The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance). A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

Подробное описание

Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.

Creatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.

Evidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.

Вмешательства

  • Пищевая добавка Creatine Bolus 5
    (Serving 1: 5 grams of creatine + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).
  • Пищевая добавка Creatine Bolus 3
    (Serving 1: 3 grams of creatine + 5 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).
  • Пищевая добавка Creatine Intermittent 5
    (Serving 1: 2.5 grams of creatine + 5.5 grams of placebo in the morning, Serving 2: 2.5 grams of creatine + 5.5 grams of placebo at least 6 hours after Serving 1).
  • Пищевая добавка Placebo
    (Serving: 8 grams of placebo in the morning; Servings 2: 8 grams of placebo at least 6 hours after Serving 1).

Первичные конечные точки

  • Whole-body lean mass (kg) [Срок оценки: baseline, week 16]
  • Muscle Hypertrophy (cm) [Срок оценки: baseline, week 16]
  • Strength (kg) [Срок оценки: baseline, week 16]
  • Endurance (number of repetitions to fatigue) [Срок оценки: baseline, week 16]
  • Power (feet) [Срок оценки: baseline, week 16]
  • Balance (Centre of Pressure) [Срок оценки: baseline, week 16]
  • Gait Speed (meters) [Срок оценки: baseline, week 16]

Критерии участия

Критерии включения

  • if you are 50 years of age and older
  • if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.

Критерии исключения

  • if you have taken creatine supplements within 30 days prior to the start of the study
  • if you have pre-existing allergies to the placebo (corn-starch maltodextrin).

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Тройное слепое
Основная цель
Лечение

Центры проведения

Канада · 1 центр
  • University of Regina — Regina

Идентификаторы

NCT: NCT06606704 · 853

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗