Effect of DASH Diet and Progressive Muscle Relaxation on Cardiovascular Risks in Postmenopausal Women

Обзор

This study will be conducted to investigate the effect of DASH diet and Progressive muscle relaxation on cardiovascular risks in postmenopausal women.

Подробное описание

Cardiovascular disease is the leading cause of morbidity and mortality in men and women, but the incidence of cardiovascular disease related deaths is higher in women than men. Hypertension is one of the leading risk factors for cardiovascular disease. Aging in both men and women is characterized by increases in blood pressure (BP), but the age-related increases are more rapid in women particularly postmenopausal women than in men.

A variety of non-pharmacologic treatments to manage stress have been found effective in reducing blood pressure and the development of hypertension. The DASH eating pattern promotes blood pressure reduction by encouraging the consumption of foods that are low in saturated fat, total fat, cholesterol, and sodium and high in potassium, calcium, magnesium, fiber, and protein. In terms of actual food choices, the DASH eating pattern encourages whole grains, fat free or low-fat dairy products, fruits, vegetables, poultry, fish, and nuts. Foods that are limited include fatty meats, full-fat dairy products, tropical oils (e.g., coconut, palm, and palm kernel oils), and sweets and sugar sweetened beverages.

The mechanism by which relaxation techniques lower blood pressure is unclear. One theory suggests that they may help lower the stress and physiologic arousal produced by the autonomic nervous system, thereby reducing blood pressure. So this study is a trial to determine the effect of DASH diet and progressive muscle relaxation in reducing cardiovascular risks in postmenopausal women.

Вмешательства

• Пищевая добавка DASH diet
  The participants will be treated with the DASH diet (1600-1800 calories/ day) for three months, in addition to antihypertensive drugs.
• Другое Progressive muscle relaxation
  The participants will be treated with progressive muscle relaxation for 30 minutes, 3 times/week for 3 months, in addition to antihypertensive drugs.
• Препарат Anti hypertensive drugs
  All participants in all groups will be treated with antihypertensive drugs as prescribed from the physician

Первичные конечные точки

• Systolic blood pressure [Срок оценки: 3 months]
• Diastolic blood pressure [Срок оценки: 3 months]
• Low density lipoprotein [Срок оценки: 3 months]
• High density lipoprotein [Срок оценки: 3 months]
• Triglyceride level [Срок оценки: 3 months]
• Total cholesterol level [Срок оценки: 3 months]

Вторичные конечные точки (1)

• Stress measurement [Срок оценки: 3 months]

Критерии участия

Критерии включения

• The participant's ages will be ranged from 50- 60 years old.
• Their body mass index will be ranged from 30-35 kg/m2.
• All women are hypertensive at least one year postmenopause.
• Their scores in perceived stress scale will be ranged from 14-40.

Критерии исключения

• Women with systolic blood pressure (SBP) >160 mmHg or diastolic blood pressure (DBP) >100mmHg.
• Women who have other known causes of hypertension, such as renal diseases.
• Women who are using sedatives or tranquilizer or antidepressant drugs.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Египет · 1 центр

• Farahnaz Ahmed Mohamed — Suez

Идентификаторы

NCT: NCT06600347 · P.T.REC/012/004059

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗