Postoperative Complications Following Skull Base Tumor Resection
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Pulmonary ultrasound examination.
- Кому может быть актуально
- Состояния в реестре: Skull Base Tumor, Postoperative Complications. Базовые параметры: от 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Postoperative Complications Following Skull Base Tumor Resection: an Observational Study
Обзор
The skull base tumor is located in the deep intracranial layer and is closely related to the brain stem and intracranial nerves. The incidence of postoperative complications after skull base tumor resection is high. Therefore, the perioperative management of skull base tumor resection is challenging.
Подробное описание
1. Postoperative pulmonary complications (PPCs), always had a 11.2%-24.6% high incidence rate. Pulmonary ultrasound (LUS), as a non-invasive diagnostic tool, has high accuracy in diagnosing pulmonary complications. Compared to traditional chest X-ray examinations, pulmonary ultrasound can identify PPCs such as atelectasis and pneumothorax earlier, and it is also more accurate in diagnosing lung consolidation.With relevant literature postoperative PACU pulmonary ultrasound is used to predict the area under the PPC curve (AUC) of 0.64 in patients within 8 days after non cardiac major surgery. Through pulmonary ultrasound examination, doctors can identify high-risk patients with pulmonary complications early after surgery. In this observational study, investigators aimed to assess the occurrence of PPCs within 7 days after surgery and evaluate the accuracy of preoperative and postoperative lung ultrasound scores in predicting PPCs. 2. Patients with skull base tumors often have a high risk of postoperative lower extremity venous thrombosis due to long operation time and many postoperative complications, such as long-term bed rest. If not treated in time, lower extremity venous thrombosis can cause disability, and severe cases can cause serious consequences such as pulmonary embolism due to thrombus detachment. In this observational study, investigators aimed to prospectively collect perioperative data and the occurrence of DVT.
Вмешательства
- Другое Pulmonary ultrasound examination
All ultrasound scans were performed by the same anaesthetists. Pulmonary ultrasound examination was performed at two time points for each patient: 20 min before starting mechanical ventilation of the lungs when patients were placed in the supine position(preoperative), 20 min after after surgery end at the time the patient was placed in the supine position (postoperative), before Intubation and after extubation Patientswere scanned in the supine position following the pulmonary ultrasound examin
Первичные конечные точки
- The incidence of postoperative pulmonary complications [Срок оценки: Postoperative 7 days]
Вторичные конечные точки (5)
- The incidence of postoperative deep venous thrombosis [Срок оценки: Postoperative 7 days]
- Cardiac injury [Срок оценки: Postoperative 7 days and 30 days]
- Postoperative pain [Срок оценки: Postoperative 2 days and 7 days]
- Overall complications [Срок оценки: Postoperative 7 days and 30 days]
- Postoperative mortality rate [Срок оценки: Postoperative 7 days and 30 days]
Критерии участия
Критерии включения
- Age 18 and above
- American Society of Anesthesiologists physical status I to III
- Undergoing elective resection of skull base tumors
- Obtaining written informed consent
Критерии исключения
- Heart failure, myocarditis, pericarditis, and cardiomyopathy
- Myocardial ischemia less than 6 months old
- Severe arrhythmia
- Severe bradycardia (heart rate below 50 beats per minute)
- Unable to complete preoperative cardiac assessment
- Severe liver dysfunction (Child Pugh C-grade)
- Severe lung diseases
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Beijing Tiantan Hospital, Capital Medical University — Пекин
Идентификаторы
NCT: NCT06587906 · 2023009