Rapid and Safe Sputum Suction Method Validation

Официальное название

Verification of the Effect of Intermittent Negative Pressure Sputum Suction Through Oral Pharyngeal Ventilation Tube in Comatose Patients

Обзор

600 comatose patients admitted to the hospital in China from June 2024 to June 2028 were randomly divided into groups A and B. Group A used intermittent negative pressure suction through oral and pharyngeal ventilation, while group B used continuous negative pressure suction through regular oral and nasal suction.

Подробное описание

Research content: (1) Selection and placement methods of oropharyngeal ventilation tubes, studying the application effects of different models and sizes of oropharyngeal ventilation tubes in critically ill patients, exploring the best placement method to improve the efficiency and safety of sputum suction operations. (2) The norms and techniques of sputum suction, the steps, techniques, and precautions of sputum suction, the depth, strength, time of insertion, and when to interrupt negative pressure, in order to minimize damage to the patient's respiratory mucosa. (3) Evaluation of patient comfort and tolerance, assessing the tolerance and potential adverse reactions of critically ill patients during oral pharyngeal intubation for sputum suction, providing a basis for optimizing sputum suction. (4) Evaluation of sputum suction effect, comparing blood oxygen saturation, respiratory distress, sputum sounds, and other indicators before and after sputum suction to evaluate the effectiveness of sputum suction.

Вмешательства

• Процедура continuous negative pressure suction
  (1) Open the mouth with a tongue depressor; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) Insert a suction tube into the mouth to aspirate phlegm.
• Процедура Intermittent negative pressure sputum suction through oral pharyngeal airway
  (1) Insert the oropharyngeal airway parallel into the oral cavity; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) The suction tube is inserted into the deep oral cavity through the middle lumen of the oropharyngeal airway; (4) Intermittent negative pressure for suction and suction of sputum

Первичные конечные точки

• Blood oxygen saturation before and after sputum aspiration [Срок оценки: Not exceeding 1 day]
• Suctioning time [Срок оценки: Not exceeding 2 minute]
• Degree of airway bleeding [Срок оценки: Not exceeding 30 minute]

Вторичные конечные точки (1)

• Patient family satisfaction [Срок оценки: Not exceeding 1 day]

Критерии участия

Критерии включения

• 1\. Clinical diagnosis of stroke; 2. Clinical diagnosis of comatose;

Критерии исключения

• 1\. Clinical diagnosis of multiple organ failure; 2. Clinical diagnosis of multiple organ bleeding;

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Простое слепое

Основная цель

Поддерживающая терапия

Центры проведения

Китай · 1 центр

• Affiliated Hospital of Nantong University — Nantong

Идентификаторы

NCT: NCT06508008 · 2024-K119-01

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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